Gold-catalyzed [5+2] cycloaddition of quinolinium zwitterions and allenamides as an efficient route to fused 1,4-diazepines

Chemical Communications : Chem Comm
Nirupam DeEun Jeong Yoo

Abstract

Herein, we demonstrate a new catalytic cycloaddition of quinolinium zwitterions involving a gold-bound allylic cation intermediate. This ligand-free higher-order cycloaddition efficiently affords a variety of fused 1,4-diazepine derivatives in a stereospecific manner at room temperature.

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Citations

Jan 23, 2019·Chemical Communications : Chem Comm·Kai GaoHanfeng Ding
Apr 11, 2019·Dalton Transactions : an International Journal of Inorganic Chemistry·Yongjia LinYuanzhi Xia
Jul 27, 2020·Chemistry : a European Journal·Barry M TrostJohnathan E Schultz
Jan 15, 2019·Accounts of Chemical Research·José L MascareñasFernando López
Dec 4, 2020·The Journal of Organic Chemistry·Frédéric VuillermetGuillaume Pelletier

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Methods Mentioned

BETA
NMR

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