Gold-catalyzed intramolecular carbocyclization of alkynyl ketones leading to highly substituted cyclic enones

Organic Letters
Tienan Jin, Yoshinori Yamamoto

Abstract

The reaction of the internal alkynyl ketones 1 (n=1) under the combined catalyst, AuCl3 and AgSbF6, gave the enones 2 in good to high yields, whereas that of the terminal alkynyl ketones 1 (n=0) under the combined catalyst, AuCl3 and AgOTf, afforded the cyclic enones 3.

Citations

Jun 13, 2009·Chemical Communications : Chem Comm·Tienan JinYoshinori Yamamoto
May 8, 2010·Chemical Communications : Chem Comm·Yoshinori YamamotoTienan Jin
May 7, 2011·Chemical Communications : Chem Comm·Nicolas KernPatrick Pale
Jun 8, 2011·Beilstein Journal of Organic Chemistry·Leping LiuGerald B Hammond
Jul 17, 2015·Chemical Reviews·Takahiko Akiyama, Keiji Mori
Jan 7, 2015·The Journal of Organic Chemistry·Youngeun Jung, Ikyon Kim
Aug 14, 2015·Organic & Biomolecular Chemistry·Maloy Nayak, Ikyon Kim
Nov 18, 2017·Chemical Science·Xinjun Tang, Armido Studer
Jun 20, 2008·Organic & Biomolecular Chemistry·Weidong Rao, Philip Wai Hong Chan
Mar 6, 2009·Organic & Biomolecular Chemistry·Volker Belting, Norbert Krause
May 26, 2010·Organic & Biomolecular Chemistry·Paul W Davies, Christelle Detty-Mambo
Aug 21, 2013·Chemistry : a European Journal·Mathieu ArnouldGérald Guillaumet
Jul 18, 2014·Chemical Communications : Chem Comm·Seetharaman Manojveer, Rengarajan Balamurugan
Oct 20, 2018·Chemical Society Reviews·Marc R BeckerCorinna S Schindler
Nov 9, 2012·Chemical Communications : Chem Comm·Asraa ZiadiRuben Martin
Mar 20, 2010·Advanced Synthesis & Catalysis·Jianwei SunSergey A Kozmin
Feb 28, 2009·Organic Letters·Carlos González-RodríguezCarlos Saá
Oct 7, 2008·The Journal of Organic Chemistry·Jhih-Meng TangRai-Shung Liu
Sep 2, 2008·The Journal of Organic Chemistry·Catelijne H M AmijsAntonio M Echavarren
Jul 11, 2008·Chemical Reviews·Zigang LiChuan He

❮ Previous
Next ❯

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.