Gold Nanocage-Based Electrochemical Sensing Platform for Sensitive Detection of Luteolin

Sensors
Xiaobao LiXiaoqin Chen

Abstract

A simple and sensitive electrochemical sensor was developed for the detection of tracelevels of luteolin. The sensoris based on a novel type of chemically modified electrode: gold nanocage (AuNCs)-modified carbon ionic liquid electrode (CILE). To construct this electrochemical sensing platform for luteolin, CILE is initially prepared by using 1-hexylpyridinium hexafluorophosphate as the binder and then AuNCs are coated on the surface of CILE to fabricate AuNCs-modified CILE (AuNCs/CILE). Electrochemical studies have shown that AuNCs/CILE can exhibit enhanced electrocatalytic activity toward the redox reaction of luteolin, therefore, the redox peak current of luteolin can be greatly improved, resulting in the high sensitivity of the developed sensor. Under the optimal conditions, the oxidation peak currents of the sensor increase linearly with an increase in the luteolin concentration in a range from 1 to 1000 nM with a detection limit of 0.4 nM, which is lower than those of most reported electrochemical luteolin sensors. Moreover, the reproducibility, precision, selectivity, and stability of this sensor are excellent. Finally, the sensing system was applied to the analysis of luteolin-spiked drug samples and the recovery in all...Continue Reading

References

Oct 1, 1995·Journal of Pharmaceutical and Biomedical Analysis·C S LiuT H Zhou
Mar 22, 2000·Journal of Agricultural and Food Chemistry·H M Merken, G R Beecher
Dec 14, 2002·Science·Yugang Sun, Younan Xia
Feb 5, 2004·Journal of Mass Spectrometry : JMS·Filip Cuyckens, Magda Claeys
Apr 7, 2004·Journal of Chromatography. a·Shu-Ping Wang, Kuo-Jun Huang
Dec 2, 2004·Nutrition and Cancer·Marian L Neuhouser
Oct 21, 2006·Archives of Biochemistry and Biophysics·Kazuki KanazawaTakashi Hashimoto
Jun 24, 2008·Accounts of Chemical Research·Sara E SkrabalakYounan Xia
Apr 22, 2009·Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.]·Ana García-LafuenteJosé Alfredo Martínez
May 3, 2011·Accounts of Chemical Research·Younan XiaPaige K Brown
Jul 2, 2016·Chemical Reviews·Kyle D GilroyYounan Xia

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Methods Mentioned

BETA
transmission
electron diffraction

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