Gold Nanoparticle-Decorated g-C3 N4 Nanosheets for Controlled Generation of Reactive Oxygen Species upon 670 nm Laser Illumination

ACS Applied Materials & Interfaces
Jiayong DaiHuang-Hao Yang

Abstract

Conventional photosensitizer-based photodynamic therapy is triggered by UV-light irradiation and depends on oxygen. However, it is hard to be applied to the deep and hypoxic tumor. To address this issue, we reported a new kind of g-C3N4 nanosheet decorated with gold nanoparticles (AuNPs), which could generate a high amount of reactive oxygen species (ROS) under a 670 nm laser irradiation in an oxygen-free environment. This synthesized semiconductor-metal heterojunction served as a superior photodynamic agent, showing prominent cancer cell-killing and tumor growth-suppressing effects in the presence of a 670 nm light and g-C3N4-AuNP composites, and its excellent ROS generation property was also validated by further bactericidal experiment.

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Citations

Jan 12, 2021·Critical Reviews in Food Science and Nutrition·Yu TianZhouli Wang
Jan 11, 2021·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·Xiaotao LiuLiangqia Guo
Jul 6, 2021·Chemical Society Reviews·Jianlei XieJong Seung Kim

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