Gold nanoparticle/polymer nanocomposite for highly sensitive drug-DNA interaction

The Analyst
F Kuralay, Arzum Erdem

Abstract

The interaction of the anticancer drug mitomycin C (MC) and DNA immobilized on gold a nanoparticle/polyvinylferrocenium (AuNP/PVF(+)) coated electrode is presented. This is the first attempt to prepare a biocompatible nanoparticle/redox polymer composite in a one-step and easy electropolymerization procedure and then use the coated electrode for MC-DNA interaction. The prepared electrode exhibits high sensitivity for the investigation of drug-DNA interaction.

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Citations

Dec 22, 2015·Dalton Transactions : an International Journal of Inorganic Chemistry·Assunta De NisiMarco Bandini
Jul 1, 2018·Electroanalysis·Filiz KuralayYaşar Bayramlı

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