Gold nanostructures as cancer theranostic probe: promises and hurdles

Nanomedicine
Bankuru Navyatha, Seema Nara

Abstract

Gold nanostructures (GNSts) have emerged as substitute for conventional contrast agents in imaging techniques and therapeutic probes due to their tunable surface plasmon resonance and optical properties in near-infrared region. Thus GNSts provide platform for the amalgamation of diagnosis and treatment (theranostics) into a single molecule for a more precise treatment. Hence, the article talks about the application of GNSts in imaging techniques and provide a holistic view on differently shaped GNSts in cancer theranostics. However, with promises GNSts also face various hurdles for their use as theranostic probe which are primarily associated with toxicity. Finally, the article attempts to discuss the challenges faced by GNSts and the way ahead that need to be traversed to place them in nanomedicine.

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Citations

Jul 7, 2021·Materials Science & Engineering. C, Materials for Biological Applications·Ganeshlenin Kandasamy, Dipak Maity

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Methods Mentioned

BETA
imaging techniques
surface plasmon resonance
light scattering
fluorescence imaging
biosensing
flow cytometry
xenografts

Software Mentioned

GNSts
Cytimmune

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