Gonadotropin hormone modulation of testosterone, immune function, performance, and behavioral trade-offs among male morphs of the lizard Uta stansburiana

The American Naturalist
Suzanne C MillsB Sinervo

Abstract

Sexual selection predicts that trade-offs maintain trait variation in alternative reproductive strategies. Experiments often focus on testosterone (T), but the gonadotropins follicle-stimulating hormone and luteinizing hormone may provide a clearer understanding of the pleiotropic relationships among traits. We assess the activational role of gonadotropins on T and corticosterone regulation in traits expressed by polymorphic male side-blotched lizards Uta stansburiana. Gonadotropins are found to enhance and suppress multiple physiological, morphological, and behavioral traits independently, as well as indirectly via T, and we demonstrate selective trade-offs between reproduction and survival. The OBY locus, a genetic marker in our model vertebrate mating system, allows characterization of the interaction between genotype and hormone treatment on male traits. Our results suggest that oo, ob, and bb males are near their physiological and behavioral capacity for reproductive success, whereas yy and by males are maintained below their physiological maximum. Both by and yy morphs show trait plasticity, and we demonstrate that gonadotropins are likely proximate effectors that govern not only trait differences between alternative mati...Continue Reading

References

Jan 1, 1978·Annual Review of Physiology·A F Bennett
Feb 1, 1987·The Journal of Experimental Zoology·J A PhillipsB L Lasley
Jun 1, 1993·Hormones and Behavior·D F DeNardo, P Licht
Apr 14, 1999·Proceedings of the National Academy of Sciences of the United States of America·S VerhulstH K Parmentier
Apr 25, 2000·The American Naturalist·José M Gómez, Regino Zamora
Dec 6, 2000·Proceedings of the National Academy of Sciences of the United States of America·K R Zamudio, B Sinervo
Jun 23, 2001·Molecular and Cellular Endocrinology·R HabertJ M Saez
Oct 11, 2001·Proceedings of the National Academy of Sciences of the United States of America·E SvenssonT Comendant
Jan 19, 2002·Proceedings. Biological Sciences·Ryan CalsbeekBarry Sinervo
Jul 5, 2002·Proceedings of the National Academy of Sciences of the United States of America·Jens Rolff, Michael T Siva-Jothy
Oct 26, 2002·Heredity·B Sinervo, E Svensson
Jun 14, 2003·Proceedings. Biological Sciences·Y Brandt
Nov 26, 2003·Journal of Evolutionary Biology·T ComendantJ Wingfield
Apr 29, 2004·Journal of Experimental Zoology. Part A, Comparative Experimental Biology·Josabel BelliureGabriele Sorci
Dec 15, 2004·General and Comparative Endocrinology·Olivier ChastelOlivier Tostain
May 17, 2006·Trends in Ecology & Evolution·Andrew SihJ Chadwick Johnson
Oct 20, 2006·Hormones and Behavior·Mark L RobertsMatthew R Evans
Jul 1, 2003·Integrative and Comparative Biology·Barry Sinervo, Ryan Calsbeek

❮ Previous
Next ❯

Citations

Oct 1, 2009·Integrative and Comparative Biology·Ellen D KettersonJoel W McGlothlin
Jan 24, 2008·Proceedings. Biological Sciences·Barry Sinervo, Andrew G McAdam
May 9, 2012·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Sandrine MeylanJean Clobert
Jan 23, 2016·Biological Reviews of the Cambridge Philosophical Society·Yong Zhi FooLeigh W Simmons
Dec 20, 2011·General and Comparative Endocrinology·Maria G PalaciosAnne M Bronikowski
Mar 31, 2010·Physiology & Behavior·Timothy A GowanDavid C Rostal
Nov 3, 2010·Molecular Ecology·Jeffrey S McKinnon, Michele E R Pierotti
Oct 1, 2011·Journal of Evolutionary Biology·P D DijkstraT G G Groothuis
Jul 13, 2016·Integrative and Comparative Biology·Mikael MokkonenSuzanne C Mills
Nov 23, 2017·Scientific Reports·Sylvain MoulheratJean Clobert
Dec 1, 2017·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·Jimena B FernándezNora R Ibargüengoytía
Jul 14, 2010·Evolution; International Journal of Organic Evolution·Lesley T LancasterBarry Sinervo
Jan 23, 2018·Journal of Experimental Zoology. Part A, Ecological and Integrative Physiology·Catherine Tylan, Tracy Langkilde
Dec 29, 2018·Journal of Morphology·Casey A GilmanDuncan J Irschick
Aug 19, 2009·Evolution; International Journal of Organic Evolution·Suzanne C MillsTanja Poikonen
Dec 7, 2016·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Lesley T LancasterRobert N Fitt
Oct 9, 2020·Biological Reviews of the Cambridge Philosophical Society·Devi Stuart-FoxClaire A McLean
Dec 25, 2016·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Eric J GangloffAnne M Bronikowski
Aug 4, 2019·Molecular and Cellular Endocrinology·S E LipshutzK A Rosvall

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.