Gonadulins, the fourth type of insulin-related peptides in decapods.

General and Comparative Endocrinology
Jan Adrianus Veenstra

Abstract

Insulin and related peptides play important roles in the regulation of growth and reproduction. Until recently three different types of insulin-related peptides had been identified from decapod crustaceans. The identification of two novel insulin-related peptides from Sagmariasus verreauxi and Cherax quadricarinatus suggested that there might a fourth type. Publicly available short read archives show that orthologs of these peptides are commonly present in these animals. Most decapods have two genes coding such peptides, but Penaeus species have likely only one and some palaemonids have three. Interestingly, expression levels can vary more than thousand-fold in the gonads of Portunus trituberculatus, where gonadulin 1 is expressed by the testis and gonadulin 2 by the ovary. Although these peptides are also expressed in other tissues, the occasionally very high expression in the gonads led to them being called gonadulins.

References

May 24, 1994·Proceedings of the National Academy of Sciences of the United States of America·C P TensenE Vreugdenhil
Dec 20, 2000·Bioinformatics·K RutherfordB Barrell
Mar 14, 2008·PLoS Biology·Irene Miguel-AliagaAlex P Gould
Mar 13, 2010·PloS One·Morgan N PriceAdam P Arkin
May 17, 2011·Nature Biotechnology·Manfred G GrabherrAviv Regev
Jun 18, 2011·General and Comparative Endocrinology·Tomer VenturaAmir Sagi
Oct 13, 2011·Molecular Systems Biology·Fabian SieversDesmond G Higgins
Dec 19, 2012·General and Comparative Endocrinology·Simon George WebsterJasmine Heloise Sharp
Jan 30, 2016·GigaScience·Linsheng SongPao Xu
Feb 7, 2018·Nature Ecology & Evolution·Julian GutekunstFrank Lyko
Jul 29, 2018·General and Comparative Endocrinology·Benjamin HerranPierre Grève
Nov 23, 2018·The Journal of Experimental Biology·Patsy S DickinsonAndrew E Christie
Jan 22, 2019·Nature Communications·Xiaojun ZhangJianhai Xiang
Nov 20, 2019·Insect Biochemistry and Molecular Biology·Jan A Veenstra, Ladislav Šimo
Feb 9, 2020·Marine Genomics·Dong Van QuyenChristopher M Austin
Apr 28, 2020·Insect Biochemistry and Molecular Biology·Joanna Kotwica-RolinskaDavid Doležel

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