PMID: 2111775Mar 1, 1990Paper

Gonococcal infection within Scotland: antigenic heterogeneity and antibiotic susceptibility of infecting strains

European Journal of Epidemiology
H YoungG A Kohiyar

Abstract

Two panels of monoclonal antibody reagents were used to serotype all strains of Neisseria gonorrhoeae isolated from four separate geographical areas serving two million of the five million Scottish population. Serotype 1B isolates accounted for 60% of the 869 strains examined and were more prevalent than 1A isolates in each geographical area. A total of 11 1A serovars and 47 1B serovars were recognised. Only two of the 11 1A serovars (Aedgkih/Arost and Aedih/Arst) were found in every centre but these accounted for over 90% of the 1A isolates. Although there was a total of 47 different 1B serovars over 80% of the isolates were accounted for by the ten most commonly encountered serovars. There were, however, marked geographical differences within both major and minor serovars. There was a highly significant difference (P less than 0.001) between protein 1A and 1B serovars with respect to their susceptibility to penicillin. Within each protein 1 type there were also differences in antibiotic susceptibility. Penicillinase-producing N. gonorrhoeae (PPNG) were found in all centres and accounted for 24 (2.8%) of the 869 isolates. The majority of the PPNG (71%) were serotype 1A and with one exception were serovar Aedih/Arst. PPNG strai...Continue Reading

References

Mar 1, 1989·The Journal of Infection·D V Coghill, H Young
Nov 1, 1988·The Journal of Antimicrobial Chemotherapy·J Heritage, P M Hawkey
Oct 1, 1985·The Journal of Antimicrobial Chemotherapy·C S Easmon

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Citations

Aug 1, 1991·Genitourinary Medicine·H YoungA McMillan
Feb 1, 1992·Genitourinary Medicine·H YoungA McMillan
Dec 1, 1994·Genitourinary Medicine·J D Ross, H Young
Jan 1, 1992·Postgraduate Medical Journal·B Watt, J G Collee
Mar 1, 1993·European Journal of Epidemiology·H YoungD H Robertson
Mar 1, 1995·International Journal of STD & AIDS·J D RossH Young

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