PMID: 8955487Dec 1, 1996Paper

Good clinical practice in patch testing: readings beyond day 2 are necessary: a confirmatory analysis. Members of the Information Network of Departments of Dermatology

American Journal of Contact Dermatitis : Official Journal of the American Contact Dermatitis Society
W J UterA Schnuch

Abstract

Despite general recommendations, patch test readings are still sometimes terminated at day 2. The consequences of failure to read patch tests after day 2 and the influence of exposure time to the patches is quantified. Patch test data from 9,946 patients with at least one positive reaction at day 2 or later and readings at both days 2 and 3 (from 21,062 patients tested between January 1, 1990, and December 31, 1993) collected by the Information Network of Departments of Dermatology in Germany were analyzed. Comparing results at days 2 and 3, 34.5% of all positive reactions appeared at day 3 only, whereas 8.3% initially judged (weakly) positive were not considered allergic at day 3. Some standard allergens showed specific patterns. Additional positive reactions and an increasing percentage of diminishing reactions can be observed at day 4 (compared with day 3). The importance of late reading(s) is emphasized by the proportion of potentially false judgments based on readings at day 2 only.

References

Oct 1, 1990·Contact Dermatitis·T Fischer
Nov 1, 1989·Contact Dermatitis·L MassoneV Isola
Oct 1, 1989·Journal of the American Academy of Dermatology·N Hjorth
Feb 1, 1989·Contact Dermatitis·A W MacfarlaneC M King
Jan 1, 1988·Journal of the American Academy of Dermatology·R L RietschelL E Rosenthal
Jan 1, 1986·Contact Dermatitis·O B ChristensenH I Maibach
Jul 1, 1982·Contact Dermatitis·D P BruynzeelB M von Blomberg-van der Flier
Sep 1, 1994·Contact Dermatitis·K BassioukasJ Hatzis
Jul 1, 1994·Contact Dermatitis·C L GohS K Ng

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Citations

Mar 12, 1999·Contact Dermatitis·J GeierT Fuchs
Jun 29, 2013·Clinics in Dermatology·Ronni WolfEleonora Ruocco
Feb 18, 2011·International Journal of Hygiene and Environmental Health·Nikolaj Drimer BergJesper Elberling
Oct 16, 2004·Fundamental & Clinical Pharmacology·Myrjam Dorothea Straube, Achim Zesch
Nov 4, 2008·Contact Dermatitis·Jacob Pontoppidan ThyssenTorkil Menné
Sep 18, 2007·Contact Dermatitis·Jacob Pontoppidan ThyssenJeanne Duus Johansen
Aug 23, 2016·Primary Care·Konstantinos Tourlas, Deepa Burman
Sep 7, 2006·Current Opinion in Allergy and Clinical Immunology·Christen M Mowad

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