Abstract
Gorham Stout disease (GSD) is a rare disease characterized by the proliferation of endothelial lined vessels and replacement of bone by fibrous tissue. The main imaging features are progressive osteolysis and cortical resorption. Temporal bone involvement is rare but presents as a destructive bone lesion that may be misinterpreted as more common lytic processes in the pediatric population, such as infection or Langerhans cell histiocytosis. GSD of the temporal bone is associated with cerebrospinal fluid (CSF) leaks, may present with otorrhea, and can mimic other causes of ear drainage. Here, we report the clinical course, imaging features, and outcomes of a 3-year-old girl with GSD of the temporal bone presenting with CSF leak initially attributed to infection.
References
Mar 4, 1999·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·P J AntonelliP S Kubilis
May 1, 2002·Skeletal Radiology·So Young YooHeung Sik Kang
Mar 18, 2003·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Elida VazquezJavier Lucaya
Mar 22, 2008·International Journal of Pediatric Otorhinolaryngology·I SalibaA Abela
May 27, 2010·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Sharon L CushingJay T Rubinstein
Mar 30, 2012·Pediatric Neurosurgery·Carmen Hernández-MarquésDaniel Azorín Cuadrillero
Jul 6, 2013·International Journal of Pediatric Otorhinolaryngology·Noriko MorimotoNobuhito Morota
Mar 4, 2014·Bone·Michael T DellingerBjorn R Olsen
Dec 30, 2015·Pediatric Blood & Cancer·Akifumi NozawaToshiyuki Fukao
Feb 13, 2016·AJNR. American Journal of Neuroradiology·K M ChevallierR K Gurgel
Aug 4, 2018·Journal of Neurosurgery. Pediatrics·Shoko YoshimotoMakoto Taniguchi
Sep 21, 2018·Insights Into Imaging·Lorenzo UggaMassimo Imbriaco
Jan 24, 2019·Pediatric Blood & Cancer·Kiersten W RicciDenise M Adams
Jun 14, 2019·International Journal of Pediatric Otorhinolaryngology·François SimonVincent Couloigner
Jan 9, 2020·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Sean StephensRaymond Chaseling