Gout: diagnosis, pathogenesis, and clinical manifestations

Current Opinion in Rheumatology
Carlos A Agudelo, C M Wise

Abstract

Gout is a common form of arthritis, in which many of the risk factors, pathogenetic mechanisms, and clinical features have been recognized for years. Nevertheless, new information has become available regarding the normal physiologic role of uric acid as an antioxidant, and greater insight has been obtained regarding the inflammatory process in acute gout. New studies have improved our understanding of the role of genetic and environmental factors responsible for hyperuricemia, and we know more about the significance of the association of hyperuricemia with other diseases. Clinically, rare complications and disease manifestations in new populations continue to be discussed, and diagnostic methods continue to be refined.

References

Apr 1, 1977·Arthritis and Rheumatism·S L WallaceT F Yü
Apr 1, 1984·Arthritis and Rheumatism·C A AgudeloE Pisko
Nov 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·B N AmesP Hochstein
Jan 12, 1999·The Biochemical Journal·J MarcilS Bourgoin
Jul 3, 1999·Annals of Internal Medicine·B F CulletonD Levy
Dec 2, 1999·Atherosclerosis·F J NietoR G Cutler
Dec 23, 1999·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·J SyrjänenA Pasternack
Jan 6, 2000·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·M PragaA Andrés
Jan 13, 2000·Chest·M A VoelkelN F Voelkel
Mar 4, 2000·Biochimica Et Biophysica Acta·T Page, M Coleman
Mar 23, 2000·Clinica Chimica Acta; International Journal of Clinical Chemistry·Y ShibutaniT Yamamoto
Apr 20, 2000·Journal of the American Society of Nephrology : JASN·David M Clive
Apr 20, 2000·Neuroscience·T LiuD J Tracey
Apr 25, 2000·Archives of Biochemistry and Biophysics·G L SquadritoW A Pryor
Apr 25, 2000·Surgery·K TsukadaY Yamamoto
Apr 27, 2000·Archives of Pathology & Laboratory Medicine·V Shidham, G Shidham
May 3, 2000·Clinical Rheumatology·Y B ParkS K Lee
May 16, 2000·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·O SchreinerE Märker-Hermann
Aug 23, 2000·AJR. American Journal of Roentgenology·C K ChenD Resnick
Nov 10, 2000·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·J Cunningham

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Citations

Oct 9, 2008·Rheumatology International·Fatma YülekSaban Simşek
Mar 16, 2007·Clinical Rheumatology·Huei-Huang HoLieh-Bang Liou
Mar 31, 2004·Radiologic Clinics of North America·Johnny U V Monu, Thomas L Pope
Jul 16, 2003·Clinical Therapeutics·Karissa Y KimSheldon X Kong
Apr 26, 2003·Joint, Bone, Spine : Revue Du Rhumatisme·Marcel-Francis Kahn
Jun 9, 2005·The Journal of Foot and Ankle Surgery : Official Publication of the American College of Foot and Ankle Surgeons·Emmanuel D LagoutarisRalph J Rothenberg
Dec 23, 2006·Annals of the Rheumatic Diseases·Stephen A WrightAllister J Taggart
Nov 1, 2012·AJR. American Journal of Roentgenology·Savvakis NicolaouPeter Munk
Aug 27, 2013·AJR. American Journal of Roentgenology·Gandikota GirishJon A Jacobson
Jun 2, 2011·Srpski arhiv za celokupno lekarstvo·Marija Radak-PerovićMirjana Zlatković-Svenda
Apr 6, 2006·Der Internist·A K TauscheH E Schröder
May 4, 2005·Drug and Chemical Toxicology·Sohail EjazChae Woong Lim
Aug 6, 2011·The Journal of Foot and Ankle Surgery : Official Publication of the American College of Foot and Ankle Surgeons·Fernando RadiceGiovanni Carcuro
May 24, 2006·Rheumatic Diseases Clinics of North America·Marc H ChoiMurray K Dalinka
Jun 28, 2002·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Holly Mattix Kramer, Gary Curhan
Apr 21, 2006·International Journal of Cardiology·Fabio De GiorgioVincenzo Arena
Nov 6, 2013·Evidence-based Complementary and Alternative Medicine : ECAM·Huiqing LvKezhi Jiang
Sep 10, 2013·Journal of Korean Medical Science·Chang-Nam SonJae-Bum Jun
Apr 22, 2004·The Journal of Immunology : Official Journal of the American Association of Immunologists·Maritza JaramilloMartin Olivier
Jun 21, 2017·American Journal of Physical Medicine & Rehabilitation·Peter Shupper, Todd P Stitik
Sep 7, 2017·BMC Complementary and Alternative Medicine·Yun Mi LeeDong-Seon Kim
May 27, 2016·Physics in Medicine and Biology·D S Rigie, P J La Rivière
Oct 9, 2004·The Journal of Biological Chemistry·Maritza JaramilloMartin Olivier
Oct 9, 2020·BMC Musculoskeletal Disorders·Simon OtterPeter Watt
Apr 28, 2021·Arthritis Research & Therapy·Yuya FujitaKiyoshi Migita

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