GPIHBP1: lipoprotein lipase's ticket to ride

Cell Metabolism
Edward A Fisher

Abstract

The mechanism of lipoprotein lipase (LPL) transport from muscle and fat cells to the luminal (apical) surface of capillaries, where it hydrolyses lipoprotein triglycerides, has remained undefined. In this issue, Davies et al. (2010) report that GPIHBP1 is required for LPL transcytosis from the basolateral to apical capillary endothelial surface.

References

Aug 9, 2008·Cell and Tissue Research·Philippe G FrankMichael P Lisanti
Dec 23, 2009·Journal of Lipid Research·Gunilla OlivecronaOlle Hernell

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