GRACE, TIMI, Zwolle and CADILLAC risk scores--do they predict 5-year outcomes after ST-elevation myocardial infarction treated invasively?

International Journal of Cardiology
Anna KozieradzkaWlodzimierz Jerzy Musial

Abstract

GRACE, TIMI, Zwolle, and CADILLAC are risk scores designed for predicting short-term outcome after acute coronary syndromes. The aim of our study was to test their utility for a prognosis of 5-year survival in a "real-life" population of patients with ST-elevation myocardial infarction (STEMI) treated with primary percutaneous coronary interventions (pPCI). Our registry consisted of consecutive patients with STEMI treated with pPCI. Five-year follow-up was performed with all-cause mortality as the end-point. Out of 505 patients (mean age 58.6±11.3 years) 32 died during the first 30 days (6.3%) and an additional 74 within 5 years (15.6%). PCI was successful in 95.2% (n=481). Prognostic values (c statistics) for predicting 5-year mortality equaled: 0.742 (CI 0.69-0.79) for the GRACE risk score, 0.727 (CI 0.67-0.78) for TIMI, 0.72 (CI 0.67-0.77) for Zwolle, and 0.687 (CI 0.63-0.74) for CADILLAC. In a univariate analysis all the scores were associated with the 5-year outcome. GRACE, TIMI, and Zwolle risk scores predicted well 5-year all-cause mortality in patients with STEMI treated with pPCI. Our data show that the usefulness of initial bedside risk assessment can be further extended for long-term follow-up.

References

Jan 1, 1976·Nephron·D W Cockcroft, M H Gault
Sep 19, 2001·JAMA : the Journal of the American Medical Association·D A MorrowE Braunwald
Oct 29, 2003·Archives of Internal Medicine·Christopher B GrangerUNKNOWN Global Registry of Acute Coronary Events Investigators
Jun 10, 2004·JAMA : the Journal of the American Medical Association·Kim A EagleUNKNOWN GRACE Investigators
Jun 16, 2007·European Heart Journal·Jean-Pierre BassandWilliam Wijns
May 27, 2008·International Journal of Cardiology·Saman RasoulUNKNOWN Zwolle Myocardial Infarction Study Group
Oct 22, 2008·The American Journal of Cardiology·Sang-Hee LeeUNKNOWN Korean Acute Myocardial Infarction Registry Investigators
Dec 3, 2008·International Journal of Cardiology·Andrew J S Coats
Jan 27, 2009·The American Journal of Cardiology·Anna KozieradzkaW J Musial

❮ Previous
Next ❯

Citations

Aug 31, 2012·Journal of Geriatric Cardiology : JGC·Alexander D SimmsChristopher P Gale
Feb 20, 2014·BMC Medical Informatics and Decision Making·Wei DongHuilong Duan
Oct 18, 2014·Advances in Medical Sciences·Karol A KamińskiWlodzimierz J Musiał
Nov 19, 2013·The Canadian Journal of Cardiology·Anibal P AbelinAlexandre S Quadros
Mar 30, 2013·American Heart Journal·Bilal BawamiaVijay Kunadian
Nov 8, 2016·Expert Review of Cardiovascular Therapy·Sergio BuccheriDavide Capodanno
Jan 29, 2019·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Xin HuangGregg W Stone
Jul 16, 2021·European Heart Journal. Acute Cardiovascular Care·Zainali S ChunawalaMelissa C Caughey

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiogenic Shock

Cardiogenic shock is a devastating consequence of acute myocardial infarction and is associated with an extremely high mortality. Here is the latest research.