PMID: 3760932Aug 1, 1986Paper

Gradation of isometric tension by different activation rates in motor units of cat flexor carpi radialis muscle

Journal of Neurophysiology
B R BottermanW J Gonyea

Abstract

Single motor units of the flexor carpi radialis (FCR) muscle were activated with a series of constant-rate stimulus trains to study the relation between the frequency of activation and isometric tension development (F-T relation). The tension produced by each stimulus train was expressed as a percentage of the maximum tension-time area (Amax) found for a given unit. Between 25 and 75% Amax a clear separation was seen in the rates needed to produce the same relative tension for the F-T curves of slow-twitch (type S) and fast-twitch (type F) units. Over the steepest portion of the F-T curve (25-50% Amax), where tension output was most sensitive to changes in activation rate, type F units required substantially higher stimulation rates (30 pps) to achieve the same relative tension output as type S units. Furthermore, the frequency range that corresponded to the steep portion of the curve was 2.3 times greater for type F units. For both type S and F units, twitch duration was deemed to be an important determinant of the F-T curve, as has been shown previously. A direct continuous relation was seen between the integrated twitch time (ITT) and the stimulus interval needed to produce 50% Amax (r = 0.94, P less than 0.001). Thus, units...Continue Reading

Citations

Aug 15, 1998·Journal of Neurophysiology·R H Lee, C J Heckman
Feb 25, 2005·Journal of Neurophysiology·Brian D Corneil, James K Elsley
May 10, 2005·Muscle & Nerve·Penelope A McNulty, Vaughan G Macefield
Jun 3, 2017·PLoS Computational Biology·Jim R Potvin, Andrew J Fuglevand
Jan 1, 1991·Biological cybernetics·A A Tax, J J Denier van der Gon
Mar 11, 2003·Journal of Applied Physiology·Minoru ShinoharaVladimir M Zatsiorsky
Mar 9, 2004·Journal of Applied Physiology·Jae Kun ShimMark L Latash
Feb 2, 2008·The Journal of Physiology·Allison HyngstromC J Heckman
Apr 14, 2006·Journal of Neurophysiology·C K Häger-RossC K Thomas
Oct 22, 2010·Journal of Neurophysiology·Samanthi C GoonetillekeBrian D Corneil
May 15, 2001·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·T M van Eijden, S J Turkawski
Nov 4, 2005·Journal of Neurophysiology·C K ThomasB Bigland-Ritchie
Apr 14, 1999·Journal of Neurophysiology·A J FuglevandB Bigland-Ritchie
Aug 25, 2007·Journal of Applied Physiology·Keith N BishopMary S Shall
May 23, 2014·Journal of Neurophysiology·Yang LiuChristine K Thomas
Oct 23, 2002·Journal of Applied Physiology·Minoru ShinoharaMark L Latash
Dec 6, 2014·Journal of Neurophysiology·Andrew J FuglevandRichard K Johns
Mar 9, 2021·PLoS Computational Biology·Akira NagamoriFrancisco J Valero-Cuevas
Sep 1, 1991·Muscle & Nerve·S A Binder-Macleod, C B Barker
Oct 1, 1995·Muscle & Nerve·J J GemperlineW Z Rymer

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