Grade 1 Vertebral Fractures Identified by Densitometric Lateral Spine Imaging Predict Incident Major Osteoporotic Fracture Independently of Clinical Risk Factors and Bone Mineral Density in Older Women.

Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research
Lisa JohanssonMattias Lorentzon

Abstract

Because prevalent vertebral fracture (VF) is a strong predictor of future fractures, they are important to identify in clinical practice as osteoporosis medications are effective and can be used to reduce fracture risk in postmenopausal women with VF. Lateral spine imaging (LSI) with dual-energy X-ray absorptiometry (DXA) can be used to diagnose VFs accurately but is not widespread in clinical practice. The prognostic value of grade 1 (20% to 25% compression) VFs diagnosed by LSI with DXA has been insufficiently studied. The aim of this study was to determine if grade 1 VF is associated with incident fracture in older women. Sahlgrenska University Hospital Prospective Evaluation of Risk of Bone Fractures (SUPERB) is a population-based study of 3028 older women from Gothenburg, Sweden. Included women were 75 to 80 years of age at baseline, answered questionnaires, and were scanned with DXA (Discovery A, Hologic, Waltham, MA, USA). LSI was used to diagnose VFs, which were classified using the Genant semiquantitative method. Cox regression models were used to estimate the association between VFs at baseline and X-ray-verified incident fractures, with adjustment for confounders. Women with a grade 1 VF (n = 264) or a grade 2-3 VF (...Continue Reading

References

Feb 1, 1992·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·C CooperL J Melton
Dec 1, 1989·Calcified Tissue International·P GärdsellJ A Nilsson
Sep 1, 1993·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·H K GenantM C Nevitt
Jul 1, 1997·Seminars in Nuclear Medicine·G M BlakeI Fogelman
Aug 18, 1997·The American Journal of Medicine·P D Ross
May 13, 1999·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·D M BlackS R Cummings
Apr 26, 2000·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·C M KlotzbuecherM Berger
Nov 23, 2000·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·H K GenantJ A Shepherd
Nov 30, 2000·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·J A ReaI Fogelman
Sep 19, 2003·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·Tamara J VokesMurray J Favus
Apr 9, 2004·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·G JiangL Ferrar
Mar 15, 2005·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Pierre D DelmasUNKNOWN IMPACT Study Group
Apr 19, 2005·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·Neil BinkleyM K Drezner
Sep 21, 2005·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·John T Schousboe, C Rowan Debold
Jun 8, 2006·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·L J MeltonR Eastell
Jul 6, 2007·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·C RouxM Girard
May 29, 2008·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Eugene V McCloskeyDiane Charlesworth
Dec 17, 2008·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·T FuerstB H Mitlak
May 26, 2011·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·L FerrarR Eastell
Sep 12, 2012·Calcified Tissue International·Daniele DiacintiSalvatore Minisola
Aug 27, 2013·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·H JohanssonJ A Kanis
Mar 18, 2015·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Daniel SundhMattias Lorentzon
Sep 10, 2015·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·Sharon H Chou, Tamara Vokes
Oct 27, 2015·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Eugene V McCloskeyJohn A Kanis
Jan 20, 2016·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·J-H LeeD-Y Kim
Sep 4, 2016·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·B Aubry-RozierD Hans
Feb 9, 2017·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·G BallaneG El-Hajj Fuleihan
Jul 20, 2017·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Brian C LentleUNKNOWN CaMos Research Group
Dec 1, 2017·Quantitative Imaging in Medicine and Surgery·Yì Xiáng J WángMarcello H Nogueira-Barbosa
Nov 6, 2018·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Richard L PrinceJohn T Schousboe
Jan 19, 2019·Journal of Internal Medicine·Mattias Lorentzon
Feb 26, 2019·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·M LorentzonD Sundh
Apr 9, 2019·Expert Opinion on Pharmacotherapy·Andreas FontalisEleftherios Tsiridis

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Citations

Jan 22, 2021·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·W F LemsUNKNOWN International Osteoporosis Foundation Fracture Working Group
Apr 21, 2021·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Eduardo KanterewiczPilar Peris
Apr 27, 2021·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Lisa Johansson, Mattias Lorentzon
Jul 28, 2021·Climacteric : the Journal of the International Menopause Society·M Chandran, A Kwee
Sep 10, 2021·Climacteric : the Journal of the International Menopause Society·T J de Villiers, S R Goldstein

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