Grade 2 meningioma and radiosurgery

Journal of Neurosurgery
Rabih AboukaisNicolas Reyns

Abstract

World Health Organization Grade 2 meningiomas are aggressive tumors associated with a high recurrence rate leading to repeated surgical procedures, which can seriously worsen a patient's neurological status. Although radiosurgery is an increasingly popular technique, its role in the management of Grade 2 meningiomas has yet to be defined. In this study the authors aimed to evaluate radiosurgery in achieving control of proven tumor progression occurring after resection of Grade 2 meningioma. This retrospective study included consecutive patients who, between 2000 and 2012, had undergone radiosurgery for radiologically proven progression of a previously surgically treated Grade 2 meningioma. Twenty-seven patients were eligible for analysis. There were 9 men and 18 women with a mean age of 59 years. The mean radiation dose was 15.2 Gy (range 12-21 Gy), and the mean target volume was 5.4 cm(3) (range 0.194-14.2 cm(3)). Thirty-four radiosurgical procedures were performed in the 27 patients. The mean progression-free survival after radiosurgery was 32.4 months among those with progression in a target irradiated volume and 26.4 months among those with progression in any intracranial meninges. With a mean follow-up of 56.4 months (rang...Continue Reading

References

Dec 31, 1997·The American Journal of Surgical Pathology·A PerryC M Lohse
Aug 30, 2000·Cancer·F YamasakiK Kurisu
Apr 27, 2005·International Journal of Radiation Oncology, Biology, Physics·Ashley W JensenPaula J Schomberg
Sep 8, 2005·Neurosurgery·Ashok Modha, Philip H Gutin
Sep 20, 2005·Journal of Neurology, Neurosurgery, and Psychiatry·W KreilG Papaefthymiou
Oct 31, 2006·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Rita Engenhart-CabillicHelmut Bertalanffy
Feb 24, 2007·Progress in Neurological Surgery·John Y K LeeL Dade Lunsford
Mar 16, 2007·Journal of Neuro-oncology·Hideyuki KanoNobuo Hashimoto
Jun 30, 2009·Journal of Neuro-oncology·Anne DurandJacques Guyotat
Dec 7, 2010·Journal of Neurosurgery·Toshinori HasegawaKouta Yoshida
Feb 24, 2012·Journal of Neuro-oncology·Albert AttiaEdward G Shaw
Jul 17, 2012·Stereotactic and Functional Neurosurgery·Jin Wook KimHee-Won Jung
Jun 6, 2013·Journal of Neuro-oncology·Michael Tin-Chung PoonGilberto Ka-Kit Leung
Sep 7, 2013·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·H TailliaG Noël

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Citations

Nov 21, 2015·Journal of Neurosurgery·Phillip A Bonney, Michael E Sughrue
Apr 25, 2016·World Neurosurgery·Michael ZhangSteven D Chang
Sep 10, 2016·Journal of Neurosurgery·Hilary P BagshawDennis C Shrieve
Sep 24, 2016·Japanese Journal of Radiology·Selcuk DemiralMurat Beyzadeoglu
Jul 10, 2019·British Journal of Neurosurgery·Lindsey S BulleidPaul A Leach
Jun 3, 2021·Cancers·Tamara IusMassimo Robiony

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