Grade 3 varicocele in fertile men: a different entity

The Journal of Urology
Marcello CocuzzaJorge Hallak

Abstract

Although varicocele size has an inverse relationship with baseline semen parameters and a direct relationship with seminal reactive oxygen species in infertile patients, to our knowledge the effect of varicocele grade in fertile men is unknown. We evaluated the impact of varicocele grade on seminal parameters, testicular size and seminal reactive oxygen species in fertile men. We prospectively evaluated 194 men from July 2004 to April 2010. Of the men 156 were fertile and classified by presence of varicocele. A total of 38 infertile patients with varicocele as the only identifiable cause of infertility comprised the control group. Physical examination, semen parameters and seminal reactive oxygen species were compared between the groups. Of 156 fertile men 43 (24.3%) had clinical varicocele, which was grade 1 to 3 in 22, 11 and 10, respectively. The remaining 113 men (72.7%) had no varicocele. Infertile men had smaller testes, decreased semen parameters and higher seminal reactive oxygen species than the fertile groups. Testicular size, reactive oxygen species and semen parameters did not differ between fertile men with vs without varicocele. Fertile men with varicocele grade 3 had higher seminal reactive oxygen species than th...Continue Reading

References

Jan 1, 1975·Acta Obstetricia Et Gynecologica Scandinavica·P Fogh-AndersenG Stakemann
Nov 1, 1965·Fertility and Sterility·J MacLeod
Feb 1, 1995·Journal of Assisted Reproduction and Genetics·M ShekarrizA Agarwal
Aug 1, 1994·The Journal of Urology·K J PintoJ P Jarow
Apr 1, 1993·The Journal of Urology·J SteckelM Goldstein
Feb 22, 2001·Urology·A KadiogluS Tellaloglu
May 1, 2001·International Journal of Urology : Official Journal of the Japanese Urological Association·D UnalO F Karatas
Jan 17, 2002·The New England Journal of Medicine·D S GuzickUNKNOWN National Cooperative Reproductive Medicine Network
Oct 10, 2006·Fertility and Sterility·Ashok AgarwalSuresh C Sikka
May 9, 2007·Fertility and Sterility·Fabio Firmbach PasqualottoAshok Agarwal
Dec 18, 2007·The Journal of Urology·Shiou-Sheng ChenYau-Huei Wei
Nov 16, 2010·Fertility and Sterility·Jose Iran LacerdaAgnaldo Pereira Cedenho

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Citations

May 29, 2012·Current Urology Reports·Laura S Merriman, Andrew J Kirsch
Oct 4, 2016·Therapeutic Advances in Urology·Ashok AgarwalChak-Lam Cho
Apr 17, 2019·Panminerva Medica·Ana D Martins, Ashok Agarwal
Jan 21, 2017·BioMed Research International·Taymour MostafaMohamed Farag

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