PMID: 6159929Nov 3, 1980Paper

Grafting of different glycosides on the surface of liposomes and its effect on the tissue distribution of 125I-labelled gamma-globulin encapsulated in liposomes

Biochimica Et Biophysica Acta
P Ghosh, B K Bachhawat

Abstract

Different glycosides were grafted on the surface of liposomes containing 125I-labelled gamma-globulin by two ways: (1) by using glycolipid and (2) by covalent coupling of p-aminophenyl-D-glycosides to phosphatidylethanolamine liposomes using glutaraldehyde. The distribution of 125I-labelled gamma-globulin was determined in mouse tissues from 5-60 min after a single injection of these liposomes. The liver uptake of encapsulated 125I-labelled gamma-globulin was highest from liposomes having galactose and mannose on the surface. Competition experiments and cross-inhibition studies indicate that this uptake are mediated by specific recognition of the surface galactose and mannose residues of liposomes by the receptors present on the plasma membrane of liver cells. Stearylamine-containing liposomes were found to be more efficient in mediating the uptake of 125I-labelled gamma-globulin by the lung, whereas in the case of spleen, phosphatidylethanolamine liposomes were more efficient. The extent of uptake of 125I-labelled gamma-globulin from all types of liposome decreases as the amount of given liposomes increases. The uptake of 125I-labelled gamma-globulin from liposomes containing asialogangliosides depends upon the phospholipid/gl...Continue Reading

References

Dec 26, 1978·Biochemistry·W CuratoloB Sears
Jul 22, 1975·Biochemical and Biophysical Research Communications·G Gregoriadis, E D Neerunjun
May 26, 1977·Biochimica Et Biophysica Acta·A Surolia, B K Bachhawat
Nov 1, 1976·Proceedings of the National Academy of Sciences of the United States of America·P StahlO Touster
Mar 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·P D StahlP H Schlesinger
Jul 11, 1977·Biochemical and Biophysical Research Communications·D T AchordW S Sly
Feb 28, 1978·Biochemical and Biophysical Research Communications·C M TsaiV Ginsburg
Aug 14, 1978·Biochemical and Biophysical Research Communications·A Surolia, B K Bachhawat
Sep 2, 1975·Biochimica Et Biophysica Acta·M M JonahY E Rahman
Feb 3, 1977·Nature·G Gregoriadis
Dec 1, 1977·Biochimica Et Biophysica Acta·R W Bussian, J C Wriston
Sep 23, 1976·The New England Journal of Medicine·G Gregoriadis
Aug 1, 1972·The Biochemical Journal·G Gregoriadis, B E Ryman
Jan 1, 1970·The Journal of Clinical Investigation·L W Hoyer, N C Trabold
Dec 1, 1967·Canadian Journal of Biochemistry·G Gregoriadis, T Sourkes
Nov 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·C C Felix, S I Weissman

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Citations

Nov 19, 1989·Molecular and Cellular Biochemistry·I AhmadB K Bachhawat
Mar 1, 1987·Biulleten' eksperimental'noĭ biologii i meditsiny·S A Burkhanov, V P Torchilin
Sep 1, 1987·Biulleten' eksperimental'noĭ biologii i meditsiny·S A BurkhanovV P Torchilin
Aug 1, 1981·Lancet·G Gregoriadis
Feb 13, 2001·International Journal of Pharmaceutics·S P VyasV Sihorkar
Jan 1, 1995·Journal of Drug Targeting·M S Wadhwa, K G Rice
Jan 1, 2001·Journal of Liposome Research·P KallinteriS G Antimisiaris
May 27, 2011·Journal of Liposome Research·Amit RathoreSanjay K Jain
Feb 1, 1984·Bioscience Reports·N Latif, B K Bachhawat
Nov 26, 2010·Journal of Controlled Release : Official Journal of the Controlled Release Society·Arehalli S ManjappaRayasa S Ramachandra Murthy
Jul 2, 2008·Expert Opinion on Drug Delivery·Eder L Romero, Maria Jose Morilla
Nov 10, 2009·Drug Development and Industrial Pharmacy·Devyani DubeSuresh P Vyas
Jan 14, 1983·Biochemical and Biophysical Research Communications·F C Szoka, E Mayhew
Feb 1, 1981·Archives of Biochemistry and Biophysics·P GhoshA Surolia
Mar 29, 2014·Journal of Biomedical Materials Research. Part a·Hwan-Seok JeongHwan-Jeong Jeong
Apr 6, 2016·Lipids in Health and Disease·Magdy M GhannamMaha Fadel
Mar 29, 2001·Progress in Lipid Research·G L Scherphof, J A Kamps
Jan 1, 1984·Immunology Letters·N Latif, B K Bachhawat
Sep 21, 1983·Biochimica Et Biophysica Acta·H H Spanjer, G L Scherphof
Jul 26, 1991·Biochimica Et Biophysica Acta·P Hug, R G Sleight
Aug 14, 1992·Biochimica Et Biophysica Acta·M C Woodle, D D Lasic
Jul 18, 1984·Biochemical and Biophysical Research Communications·E F SommermanP R Cullis
Feb 17, 2006·Mechanisms of Ageing and Development·Sibani Sarkar, Nirmalendu Das
Oct 6, 2009·Journal of Controlled Release : Official Journal of the Controlled Release Society·Xue YingQiang Zhang

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