PMID: 9421750Jan 1, 1997Paper

Grafting of PEO to glass, nitinol, and pyrolytic carbon surfaces by gamma irradiation

Journal of Biomedical Materials Research
T McPhersonK Park

Abstract

Glass, nitinol, and pyrolytic carbon surfaces were grafted with poly (ethylene oxide) (PEO) and PEO-containing Pluronic surfactants by gamma irradiation. These substrates were coated with a primer layer of trichlorovinylsilane (TCVS), which allows grafting of organic polymers. The TCVS-coated substrates were adsorbed with PEO or Pluronics and exposed to 0.3 Mrad of gamma radiation to graft the polymer to the surface. PEO-grafted substrates were characterized by contact angle measurement, X-ray photoelectron spectroscopy, fibrinogen adsorption, and platelet adhesion and activation. Surface modification with PEO reduced fibrinogen adsorption by as much as 99%. Platelet adhesion was significnatly reduced or prevented on the modified surfaces. Protein- and platelet-resistance effects were independent of hydrophilicity of the PEO-grafted surfaces. Polymer grafting by gamma radiation to TCVS-coated substrates provides a facile process to improve thromboresistance of inorganic biomaterials.

References

May 1, 1992·Journal of Biomedical Materials Research·G Rollason, M V Sefton
Apr 1, 1992·Journal of Biomedical Materials Research·G P LópezT A Horbett
Jul 1, 1991·Journal of Biomedical Materials Research·N P Desai, J A Hubbell
May 1, 1991·Journal of Biomedical Materials Research·S OmokawaY Nosé
Jun 1, 1991·Journal of Biomedical Materials Research·S C LinS W Kim
Oct 1, 1990·Journal of Biomedical Materials Research·K HayashiN Yamamoto
Jul 1, 1987·Journal of Biomedical Materials Research·M S Payne, T A Horbett
Mar 1, 1994·Journal of Biomedical Materials Research·K W van der Kamp, W van Oeveren
Nov 1, 1993·Journal of Biomedical Materials Research·G R Llanos, M V Sefton
Mar 1, 1993·AJR. American Journal of Roentgenology·J C Palmaz
Jan 1, 1993·Journal of Biomaterials Applications·Y C TsengK Park

❮ Previous
Next ❯

Citations

Aug 13, 2011·Journal of Materials Science. Materials in Medicine·Tingting ZhaoTao Zhang
Jan 27, 2004·Biomaterials·Hong ChenHeather Sheardown
Dec 21, 2013·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Keely HeintzJoseph McGuire
Jan 2, 2014·Colloids and Surfaces. B, Biointerfaces·Chiao-Tzu SuHsien-Yeh Chen
Aug 17, 2002·Journal of Biomaterials Science. Polymer Edition·Jae Hyung Park, You Han Bae
Dec 5, 2002·Journal of Biomaterials Science. Polymer Edition·Hee Jung LeeYoung Ha Kim
Mar 27, 2001·Journal of Biomaterials Science. Polymer Edition·K ParkN L Eigler
Sep 22, 1999·Journal of Biomedical Materials Research·A Kidane, K Park
Jan 13, 2004·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Yu Chi Wang, Chia-Chi Ho
Sep 30, 2008·Pharmaceutical Development and Technology·Yuan-Ching TaiD Q Wang
Nov 7, 2014·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Pingsheng LiuJian Shen
Feb 9, 2002·Journal of Biomedical Materials Research·Hyung Dal ParkNobuhiko Yui
May 8, 2007·Journal of Materials Science. Materials in Medicine·D Sakthi KumarYasuhiko Yoshida
Mar 28, 2009·Journal of Biomaterials Science. Polymer Edition·Hsi-Yi Yeh, Jui-Che Lin
Jan 9, 2014·Biotechnology and Applied Biochemistry·Julie A AuxierJoseph McGuire
Sep 4, 2008·Langmuir : the ACS Journal of Surfaces and Colloids·Rosalynn Quiñones, Ellen S Gawalt
Oct 3, 2009·Langmuir : the ACS Journal of Surfaces and Colloids·Raechelle A D'Sa, Brian J Meenan
Jul 14, 2018·Langmuir : the ACS Journal of Surfaces and Colloids·Antoine Venault, Yung Chang
Mar 25, 2008·Journal of Colloid and Interface Science·Yuan-Ching TaiJennifer A Neff
Aug 1, 2000·Colloids and Surfaces. B, Biointerfaces·A KidaneK Park

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.