Granular cell tumor of the breast: a case report and review of literature.

Cases Journal
Vanja A FilipovskiBlagica Dukova

Abstract

A 22-year-old female patient presented with a breast mass lesion with a clinical suspicion of a fibroadenoma. Histological evaluation revealed a rare benign neoplasm - granular cell tumor.Granular cell tumor is rare neoplasm that may arise in virtually any body site, and in 5% it occurs in the breast. The histogenesis of this tumor is still rather controversial and currently the most acceptable theory is a Schwann cell origin. The main histological feature is granular cytoplasm of the tumor cells.From a clinical point of view there is a similarity between granular cell tumor and mammary carcinoma on mammography and ultrasound. Pathohistologically, sometimes, differential diagnostic difficulties exist concerning apocrine carcinoma, histiocytic lesions and metastatic neoplasms.

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Citations

Feb 14, 2012·Radiología·R Escudero EstebanP Yáñez Fernández
Mar 14, 2016·International Journal of Surgery Case Reports·A SanguinettiN Avenia
Oct 14, 2011·The Journal of Dermatology·Youichi OgawaShinji Shimada
May 28, 2014·Journal of Surgical Oncology·Sarah J CoatesRache M Simmons
Dec 30, 2014·Journal of Medical Case Reports·Nawal HammasAfaf Amarti
Jun 8, 2011·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Nicole De SimoneCarla Christy

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