Granulatamides A and B, cytotoxic tryptamine derivatives from the soft coral Eunicella granulata

Journal of Natural Products
Fernando ReyesRogelio Fernandez

Abstract

Two new tryptamine derivatives, granulatamides A (1) and B (2), were isolated from the 2-propanol extract of the soft coral Eunicella granulata. Their structures were determined on the basis of detailed spectroscopic analysis and comparison with previously published data for similar compounds. Both compounds showed moderate in vitro cytotoxicity against a panel of 16 human tumor cell lines.

References

Jul 4, 1990·Journal of the National Cancer Institute·P SkehanM R Boyd
Feb 5, 2005·Natural Product Reports·John W BluntMichele R Prinsep

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Citations

Feb 6, 2008·Natural Product Reports·John W BluntMichèle R Prinsep
Aug 20, 2015·Marine Drugs·Natalie Netz, Till Opatz
May 28, 2009·Natural Product Reports·Minoru Ishikura, Koji Yamada
Aug 18, 2010·Natural Product Reports·Annika PutzHeike Wägele
Aug 14, 2013·Chemistry & Biodiversity·Chenghai GaoBo Chen
Sep 26, 2020·Natural Product Research·Nourhan Hisham ShadyMohamed Salah Kamel
Jan 8, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Dario MatuljaDean Marković
Feb 10, 2021·Nature Ecology & Evolution·Ty N F RoachCrawford Drury

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