Granulocytic sarcoma of the uterine cervix

International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society
J W LeeW I Yang

Abstract

Granulocytic sarcoma (GS) is a rare manifestation of leukemia and has been reported in 3-5% of acute myelogenous leukemia (AML) patients. GS in the uterine cervix is very rare and is also called chloroma because of its greenish appearance. We present the case of a patient whose disease relapsed as chloroma of the uterine cervix after bone marrow transplantation (BMT). She remained in continuous complete remission for 2 years after allogeneic BMT. However, she visited the hospital because of painless vaginal bleeding. She was diagnosed as having chloroma by cervical smear and colposcopically directed biopsy of the cervix. Systemic chemotherapy was administered on the presumption that myelogenous leukemia had recurred as chloroma, and a good clinical response was achieved. We describe the first case of AML that relapsed as chloroma of the uterine cervix after complete remission of the AML, which had complete response to only systemic chemotherapy.

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Citations

Jul 14, 2012·Archives of Gynecology and Obstetrics·Harinder GillYok-Lam Kwong
Oct 14, 2010·Hinyokika kiyo. Acta urologica Japonica·Masahiro NittaToshiro Terachi
May 19, 2006·American Journal of Clinical Pathology·Mar Garcia GarciaL Jeffrey Medeiros
May 21, 2016·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·Sara Mathew GeorgeAshok Kumar Malik
Jul 16, 2005·Gynecologic Oncology·Bhuvan PathakWalter H Gotlieb
Feb 17, 2015·Case Reports in Obstetrics and Gynecology·Gaurang ModiMalay Sarkar
Mar 5, 2019·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Karishma P RamlakhanSjarlot G Kooi

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