Granulomatous amebic encephalitis in a multivisceral transplant recipient

European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies
O MendezSasa Zivković

Abstract

A 40-year-old man with multivisceral allograft developed acutely right-sided numbness 9 months after transplantation. Cranial magnetic resonance imaging (MRI) showed a small left parietal lesion, and cerebrospinal fluid analysis was unremarkable. Stereotactic brain biopsy was non-diagnostic. The patient continued to deteriorate, developed cerebral edema and died at 13 days after the onset of symptoms. Unexpectedly, autopsy demonstrated acanthamebic encephalitis. This case highlights diagnostic difficulties encountered with amebic encephalitis and expands the spectrum of opportunistic central nervous system (CNS) infections in solid and visceral organ transplant recipients.

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Citations

Nov 6, 2012·Neuroimaging Clinics of North America·Ayca AkgozThomas C Lee
Nov 26, 2009·Neurologic Clinics·Sasa A Zivković, Hoda Abdel-Hamid
Apr 20, 2007·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Sasa Zivković
Sep 10, 2013·Transplant Infectious Disease : an Official Journal of the Transplantation Society·M J SatlinR Soave
Aug 28, 2009·Clinical Transplantation·Sasa A ZivkovićKareem M Abu-Elmagd
Jan 10, 2017·Transplant Infectious Disease : an Official Journal of the Transplantation Society·Max N BrondfieldJennifer M Babik
Jul 28, 2016·BJR Case Reports·Matthew William LukiesNoriyuki Tomiyama
Oct 28, 2019·Experimental Parasitology·Sonali K KalraUjjala Ghoshal

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