PMID: 8454784Jan 1, 1993Paper

Granulomatous dermatitis to iron oxide after permanent pigmentation of the eyebrows

The Journal of Dermatologic Surgery and Oncology
E I Rubianes, J L Sánchez

Abstract

Tattooing with iron oxide pigment is used to create a permanent line along the eyelid margins and to cause permanent pigmentation of the eyebrows. However inflammatory sequelae can occur. To present the development and treatment of a granulomatous inflammation as a sequela of iron oxide tattooing in the eyebrows. A skin biopsy was performed, Histopathologic examination revealed deposits of reddish-brown pigment and a superficial dermal infiltrate consisting of lymphocytes and giant multinucleated cells (Langhan's and foreign body). A patient developed a granulomatous reaction to iron oxide after undergoing permanent pigmentation of the eyebrows. Treatment with systemic and topical steroids resulted in marked improvement at 6-month follow-up. This is an unusual complication. A skin test should be performed on any patient who is to undergo tattooing with iron oxide pigment.

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Citations

Nov 12, 2014·American Journal of Clinical Dermatology·Carolina Simunovic, Michi M Shinohara
Sep 22, 2009·The Science of the Total Environment·Giovanni ForteBeatrice Bocca
Feb 10, 1998·Contact Dermatitis·R TreudlerC E Orfanos
Mar 1, 1996·Contact Dermatitis·W HemmerR Jarisch
Apr 18, 2000·Journal of the American Academy of Dermatology·H P SchwarzeJ Bazex
Dec 1, 1996·Plastic and Reconstructive Surgery·H M Goldberg
May 29, 2004·The Journal of Craniofacial Surgery·Eddy M van der VeldenM Frans Noorman van der Dussen
May 24, 2008·International Journal of Cosmetic Science·A B Lansdown
Sep 10, 1998·International Journal of Dermatology·E M van der VeldenH J Hulsebosch
Dec 3, 1999·The British Journal of Dermatology·W M PorterR C Staughton
Dec 1, 2007·Journal of Cosmetic Dermatology·José M MartínEsperanza Jordá
Aug 27, 2013·The American Journal of Dermatopathology·Chee K Thum, Asok Biswas
Aug 1, 1998·Contact Dermatitis·R GalloM Guarrera
Nov 14, 2002·Journal of the European Academy of Dermatology and Venereology : JEADV·A Ghorpade
May 3, 2021·Survey of Ophthalmology·Sonali T NagendranRaman Malhotra

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