Granulomatous inflammation and nerve necrosis in a case of apparent idiopathic vocal fold paralysis: report of a case

The Laryngoscope
Behrooz A Torkian, Roger L Crumley

Abstract

We will present clinical and pathologic findings of the recurrent laryngeal nerve of a 54-year-old man with apparent idiopathic vocal fold paralysis and discuss clinical and scientific implications of these findings. Our design is in the format of a case report with emphasis on the clinical, intraoperative, histologic, and neuropathologic findings, followed by a discussion of contemporary theories of idiopathic unilateral vocal fold immobility and the implications of our findings. A 54-year-old man presented with a 2-year history of unilateral vocal fold motion impairment (VFMI) after an upper respiratory infection. Radiographic and laboratory data revealed no organic cause. The patient clinically appeared to have a classical unilateral vocal fold paralysis and had previously undergone collagen injection and medialization thyroplasty, each with only temporary improvement of voice. We performed ansa cervicalis-recurrent laryngeal nerve anastomosis. Intraoperative dissection revealed an indurated and thickened section of nerve approximately 15 mm in length, located at the beginning of the intralaryngeal segment, near the cricothyroid joint. Segments of this nerve were submitted for histologic evaluation, revealing necrosis with g...Continue Reading

References

May 11, 1978·The New England Journal of Medicine·K G WarrenJ Subak-Sharpe
Jun 1, 1990·The American Journal of Medicine·R H Flowers, D S Kernodle
Jan 1, 1989·Acta Neuropathologica·J R Martin, S Suzuki
Jul 1, 1970·The Laryngoscope·F W Parnell, J H Brandenburg
Jul 1, 1980·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·K K AdourR L Hilsinger
Sep 1, 1982·The Laryngoscope·R L Crumley
Nov 1, 1982·The Annals of Otology, Rhinology, and Laryngology·P H Ward, G Berci
Jun 1, 1980·Archives of Otolaryngology·H Berry, R L Blair
Mar 1, 1994·Journal of Voice : Official Journal of the Voice Foundation·R L Crumley
Jan 1, 1996·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·E BachorT Hacki
Apr 1, 1997·The American Journal of Dermatopathology·J T Worrell, C J Cockerell
Mar 3, 1998·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·H H RamadanS Avery
Apr 25, 2000·The Annals of Otology, Rhinology, and Laryngology·R L Crumley
Aug 5, 2000·Otolaryngologic Clinics of North America·G Woodson
Sep 12, 2001·Acta Neurologica Scandinavica·S C TangP K Yip
Nov 23, 2001·Acta Oto-laryngologica·J T Vrabec, D A Payne
Jan 5, 2002·Auris, Nasus, Larynx·Eiji YumotoTakahiko Yamagata

❮ Previous
Next ❯

Citations

Feb 29, 2008·Thyroid : Official Journal of the American Thyroid Association·Shun Yu ChiPeter E Goretzki
Jul 31, 2007·Journal of the Neurological Sciences·Mario ArmaniBruno Tavolato

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.