Grape pomace flour alleviates Pseudomonas aeruginosa-induced hepatic oxidative stress in grass carp by improving antioxidant defense

Microbial Pathogenesis
Carine F SouzaB Baldisserotto

Abstract

Pseudomonas aeruginosa is a Gram-negative opportunistic bacterial pathogen in aquaculture systems being associated to extensive liver damage caused by oxidative stress in both marine and freshwater fish. Dietary supplementation with natural antioxidants is considered a rational strategy to prevent hepatic diseases involved with oxidative stress. Bio-residues resulting from the wine industry, such as grape pomace, are potential sources of bioactive phenolic compounds that can be applied as supplement for animal production. Thus, the aim of this study was to evaluate whether dietary supplementation with grape pomace flour (GPF) was able to prevent or reduce the hepatic oxidative damage of grass carp, Ctenopharyngodon idella, experimentally infected by P. aeruginosa. Hepatic reactive oxygen species (ROS), metabolites of nitric oxide (NOx), thiobarbituric acid reactive substances, and protein carbonylation levels were higher in fish experimentally infected by P. aeruginosa compared to the control group. Hepatic superoxide dismutase and catalase activities and antioxidant capacity against peroxyl radical levels were also higher in fish experimentally infected by P. aeruginosa compared to the control group. Dietary supplementation wi...Continue Reading

References

Jun 1, 1979·Analytical Biochemistry·H OhkawaK Yagi
Jan 1, 1984·Methods in Enzymology·H Aebi
Jan 1, 1994·Methods in Enzymology·A Z Reznick, L Packer
Dec 28, 2010·Clinical Biochemistry·Etiane TatschRafael Noal Moresco
Apr 28, 2012·Nutrition Reviews·Barry Halliwell
Sep 3, 2013·Antioxidants & Redox Signaling·Claudia N Paiva, Marcelo T Bozza
Feb 8, 2014·Biotechnology and Applied Biochemistry·Prabhakar MishraNatarajan Chandrasekaran
Feb 15, 2014·Colloids and Surfaces. B, Biointerfaces·John ThomasNatarajan Chandrasekaran
May 23, 2014·Current Biology : CB·Michael Schieber, Navdeep S Chandel
Dec 3, 2014·Chemico-biological Interactions·Volodymyr I Lushchak
Nov 6, 2015·International Journal of Molecular Sciences·Sha LiYibin Feng
Feb 13, 2016·Food Chemistry·Carolina BeresLourdes M C Cabral
Dec 29, 2016·Microbial Pathogenesis·Angelisa H BiazusMarcel M Boiago
Feb 19, 2017·Biochemical and Biophysical Research Communications·Michael M Gaschler, Brent R Stockwell
Nov 22, 2017·Current Opinion in Toxicology·Bennett Van HoutenMauricio Camargo
Mar 6, 2018·Food Chemistry·Carla M PeixotoIsabel C F R Ferreira
Jun 19, 2018·Cells, Tissues, Organs·Reginaldo FranklinMarcio Antonio Babinski
Jul 1, 2018·Free Radical Biology & Medicine·Jose ViñaMari Carmen Gomez-Cabrera
Oct 20, 2018·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Rui JiaGuojun Yin
Oct 27, 2018·Animals : an Open Access Journal From MDPI·Marco IannacconeGiuseppe Martino

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