Grape skin improves antioxidant capacity in rats fed a high fat diet.

Nutrition Research and Practice
Su-Jin LeeJung-Sook Seo

Abstract

This study was conducted to investigate the effect of dietary grape skin on lipid peroxidation and antioxidant defense system in rats fed high fat diet. The Sprague-Dawley rats were fed either control (5% fat) diet or high fat (25% fat) diet which was based on AIN-93 diet for 2 weeks, and then they were grouped as control group (C), control + 5% grape skin group (CS), high-fat group (HF), high fat + 5% grape skin group (HFS) with 10 rats each and fed corresponding diets for 4 weeks. The hepatic thiobarbituric acid reacting substances (TBARS) were increased in high fat group as compared with control group, but reduced by grape skin. The serum total antioxidant status, and activities of hepatic catalase and superoxide dismutase, xanthine oxidase and glucose-6-phosphatase were increased by supplementation of grape skin. Glutathione peroxidase activity was significantly higher in CS group than in C group. Grape skin feeding tended to increase the concentration of total glutathione, especially in control group. The ratio of reduced glutathione to oxidized glutathione was lower in high fat groups than in control groups. The ratio was increased by dietary supplementation of grape skin in control group. These results suggest that dieta...Continue Reading

References

Jun 1, 1979·Analytical Biochemistry·H OhkawaK Yagi
Apr 1, 1976·Biochemical Medicine·K Yagi
Mar 13, 1998·The American Journal of Clinical Nutrition·D B West, B York
Jun 25, 1999·Free Radical Biology & Medicine·R ReC Rice-Evans
Nov 24, 1999·Free Radical Biology & Medicine·H Sies
Aug 18, 2001·The British Journal of Nutrition·P Evans, B Halliwell
Oct 26, 2001·Free Radical Biology & Medicine·C Ramirez-TortosaG G Duthie
Aug 21, 2002·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·S O Olusi
Oct 4, 2002·Nutrition·Yun-Zhong FangGuoyao Wu
Nov 1, 2002·Journal of Cardiovascular Pharmacology·Jianhua CuiDipak K Das
May 8, 2003·Bioresource Technology·C NegroA Miceli
Oct 18, 2003·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Francesca ScarlattiRiccardo Ghidoni
Dec 23, 2003·Cell Biology and Toxicology·R AcquavivaA Vanella
Jan 10, 2004·The Journal of Neuroscience Nursing : Journal of the American Association of Neuroscience Nurses·Susan M Calne
May 26, 2004·Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy·Helene PelicanoPeng Huang
Aug 18, 2004·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·Hideharu FukaoJunichiro Yamamoto
Dec 16, 2004·The Journal of Clinical Investigation·Shigetada FurukawaIichiro Shimomura
Dec 29, 2004·Physiology & Behavior·George A BrayBarry M Popkin
Apr 15, 2005·Molecular Nutrition & Food Research·Dominique DelmasNorbert Latruffe
Jan 13, 2006·Biochemical and Biophysical Research Communications·Yan ZhangBaofeng Yang
Jan 26, 2006·American Journal of Physiology. Endocrinology and Metabolism·Hui-Chen SuJan-Kan Chen
Mar 7, 2006·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·A Kasdallah-GrissaS El-Fazaa
Aug 4, 2006·International Journal of Cardiology·Jonica CampoloOberdan Parodi
Aug 31, 2006·Journal of Agricultural and Food Chemistry·M FalchiDipak K Das
Oct 13, 2006·Pulmonary Pharmacology & Therapeutics·Göksel SenerNursal Gedik
Apr 19, 2007·Molecular Nutrition & Food Research·Hanne FrederiksenSalka E Rasmussen
May 4, 2007·The British Journal of Nutrition·Chin-Lin Hsu, Gow-Chin Yen
Jun 16, 2007·Epidemiologic Reviews·Benjamin Caballero
Jan 22, 2009·Journal of Vascular Research·Socorro Vanesca Frota MadeiraValérie B Schini-Kerth
Feb 12, 2009·Pakistan Journal of Biological Sciences : PJBS·N YassaA Hadjiakhoondi
Mar 21, 2009·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·K K R RochaE L B Novelli
Mar 1, 2007·Indian Journal of Clinical Biochemistry : IJCB·Vidya AkhileshwarSurendra S Katyare

❮ Previous
Next ❯

Citations

Jan 21, 2016·Oxidative Medicine and Cellular Longevity·Csaba CsonkaTamás Csont
Apr 16, 2013·Journal of the Science of Food and Agriculture·Sylwia Mildner-Szkudlarz, Joanna Bajerska
Jul 19, 2012·Journal of the Science of Food and Agriculture·Sylwia Mildner-SzkudlarzDanuta Górecka
Oct 24, 2013·BioMed Research International·Suja Rani SasidharanAmit Agarwal
Jun 15, 2016·Journal of Exercise Nutrition & Biochemistry·Seyed Reza EmamiAliasghar Ravasi
Dec 18, 2013·BMC Complementary and Alternative Medicine·Yan LiangXiaofeng Ma
Oct 25, 2016·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Sudhakara GujjalaSaralakumari Desireddy
Feb 26, 2016·European Journal of Nutrition·Nathalie AubervalSéverine Sigrist
Feb 2, 2018·Biotechnic & Histochemistry : Official Publication of the Biological Stain Commission·G SudhakaraD Saralakumari
Nov 30, 2011·Nutrition Research and Practice·Ji Eun LeeJung-Hyun Kim
Feb 21, 2013·Nutrition Research and Practice·Soo-Kyong Choi, Jung-Sook Seo
Mar 14, 2012·Nutrition Research and Practice·Soo-Kyong ChoiJung-Sook Seo
Jul 14, 2020·Evidence-based Complementary and Alternative Medicine : ECAM·Erieg A MohamedRomeo T Cristina
Jul 1, 2016·Journal of Food and Drug Analysis·Sudhakara GujjalaSaralakumari Desireddy

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.