Graphene Oxide-Coated Surface: Inhibition of Bacterial Biofilm Formation due to Specific Surface-Interface Interactions

ACS Omega
Nisha YadavBimlesh Lochab

Abstract

Graphene oxide (GO) is a promising and remarkable nanomaterial that exhibits antimicrobial activity due to its specific surface-interface interactions. In the present work, for the first time, we have reported the antibacterial activity of GO-coated surfaces prepared by two different methods (Hummers' and improved, i.e., GOH and GOI) against bacterial biofilm formation. The bacterial toxicity of the deposited GO-coated surfaces was investigated for both Gram-negative (Escherichia coli) and Gram-positive (Staphylococcus aureus) models of bacteria. The mechanism of inhibition is different on the coated surface than that in suspension, as determined by measurement of the percentage inhibition of biofilm formation, Ellman's assay, and colony forming unit (CFU) studies. The difference in the nature, degree of oxidative functionalities, and size of the synthesized GO nanoparticles mitigates biofilm formation. To better understand the antimicrobial mechanism of GO when coated on surfaces, we were able to demonstrate that beside reactive oxygen species-mediated oxidative stress, the physical properties of the GO-coated substrate effectively inactivate bacterial cell proliferation, which forms biofilms. Light and atomic force microscopy...Continue Reading

References

Jan 1, 1991·Clinical Microbiology Reviews·J R Johnson
May 21, 1999·Science·J W CostertonE P Greenberg
May 4, 2000·Progress in Lipid Research·X Wang, P J Quinn
Feb 13, 2001·Microbiology·I Sutherland
Apr 5, 2002·Clinical Microbiology Reviews·Rodney M Donlan, J William Costerton
Aug 27, 2002·Emerging Infectious Diseases·Rodney M Donlan
Oct 3, 2002·Biochemical and Biophysical Research Communications·M C Becerra, I Albesa
Oct 23, 2004·Science·K S NovoselovA A Firsov
Dec 4, 2004·Nature Medicine·Stuart B Levy, Bonnie Marshall
May 17, 2005·Current Medicinal Chemistry·M ValkoM T D Cronin
Feb 4, 2006·Science·Andre NelNing Li
Aug 15, 2006·Environmental Science & Technology·Delina Y LyonPedro J J Alvarezt
Mar 7, 2007·Journal of Biomedical Materials Research. Part a·Moran AvivMeital Zilberman
Jul 27, 2007·Nature·Dmitriy A DikinRodney S Ruoff
Oct 18, 2007·JAMA : the Journal of the American Medical Association·R Monina KlevensUNKNOWN Active Bacterial Core surveillance (ABCs) MRSA Investigators
Jan 22, 2008·Nature Materials·Ashavani KumarGeorge John
Jun 3, 2008·Langmuir : the ACS Journal of Surfaces and Colloids·Seoktae KangMenachem Elimelech
Sep 11, 2008·Nano Letters·Jeremy T RobinsonBrian H Houston
Feb 10, 2009·Nano Letters·K Andre MkhoyanManish Chhowalla
May 11, 2010·Cold Spring Harbor Perspectives in Biology·Thomas J SilhavySuzanne Walker
Jul 3, 2010·ACS Nano·Wenbing HuChunhai Fan
Aug 25, 2010·ACS Nano·Daniela C MarcanoJames M Tour
Oct 12, 2010·ACS Nano·Omid Akhavan, Elham Ghaderi
Mar 10, 2011·Nanomedicine·Liangzhu Feng, Zhuang Liu
Jan 26, 2012·FEMS Microbiology Reviews·Olaya Rendueles, Jean-Marc Ghigo
Mar 17, 2012·International Journal of Antimicrobial Agents·Sylvie Buffet-BataillonAnne Jolivet-Gougeon
Jul 26, 2012·Langmuir : the ACS Journal of Surfaces and Colloids·Shaobin LiuYuan Chen
Apr 9, 2013·ACS Nano·Chaenyung ChaAli Khademhosseini
Jan 23, 2015·International Journal of Nanomedicine·Sitansu Sekhar NandaDong Kee Yi
Mar 17, 2015·ACS Applied Materials & Interfaces·Carolina ParraPatricio Häberle
Jun 21, 2015·ACS Nano·François PerreaultMenachem Elimelech
Nov 18, 2015·Journal of Nanobiotechnology·Carolina ParraPatricio Villalobos
Jun 23, 2016·Frontiers in Microbiology·Jason N PayneRajalingam Dakshinamurthy
Dec 23, 2016·ACS Applied Materials & Interfaces·Fengming ZouJaebeom Lee
Mar 1, 2017·International Journal of Nanomedicine·Linlin WangLongquan Shao

❮ Previous
Next ❯

Citations

Apr 3, 2020·Archives of Toxicology·Feng XiaoliShao Longquan
Jun 30, 2019·Environmental Science and Pollution Research International·Hussam FallatahKonstantinos Gkatzionis
Oct 18, 2020·Antibiotics·Cecilia MartiniMaurizio Sanguinetti
Nov 28, 2020·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Santosh PanditIvan Mijakovic
Feb 3, 2021·Colloids and Surfaces. B, Biointerfaces·Guihua CaoJianbin Guo
Dec 20, 2020·Colloids and Surfaces. B, Biointerfaces·Tahereh Seifi, Ali Reza Kamali
Apr 13, 2021·Frontiers in Microbiology·Lauris EvaristeMaialen Barret
Jul 10, 2021·ACS Applied Materials & Interfaces·Andreia T PereiraInês C Gonçalves
Jan 30, 2019·Environmental Science & Technology·Rebecca A HillNicholas C Fitzkee

❮ Previous
Next ❯

Methods Mentioned

BETA
light microscopy
optical microscopy
X-ray
scanning electron microscopy
AFM
light
Assay

Related Concepts

Related Feeds

Biofilm & Infectious Disease

Biofilm formation is a key virulence factor for a wide range of microorganisms that cause chronic infections.Here is the latest research on biofilm and infectious diseases.

Biofilms

Biofilms are adherent bacterial communities embedded in a polymer matrix and can cause persistent human infections that are highly resistant to antibiotics. Discover the latest research on Biofilms here.