Abstract
An analysis of 59 patients who underwent total thyroidectomy for the treatment of Graves' disease over a 6-year period was conducted in order to assess the current indications and identify any specific factors that may influence the patient's decision to opt for surgical treatment. A comparison of outcomes between the current study and a similar one from Hong Kong was also attempted. Patient preference was the most common reason for opting for surgery over radioactive iodine in both studies. Other indications for surgery, such as Graves' ophthalmopathy, patient refusal for radioactive iodine, large goitre with pressure symptoms, planning for pregnancy, young age, and intolerance to anti-thyroid drugs, were also similar in the two groups. There were no statistically significant differences in laryngeal nerve palsy between the two groups. The rates of permanent hypoparathyroidism in patients in Hong Kong and in the present study were 5.4% and 5.1%, respectively. No patient in either study had recurrent Graves' disease after total thyroidectomy. Our findings confirmed that patient preference is the leading indication for surgery, implicating a continuous misconception of radioactive substances and increasing confidence in surgical...Continue Reading
References
Dec 1, 1977·Clinical Endocrinology·W M TunbridgeP A Smith
Apr 1, 1990·The Journal of Clinical Endocrinology and Metabolism·A BelfioreR Vigneri
Jun 1, 1974·The Journal of Clinical Endocrinology and Metabolism·B M DobynsD V Becker
May 4, 2000·The Journal of Surgical Research·T K PalitD M Miltenburg
Jun 24, 2000·World Journal of Surgery·I R Gough, D Wilkinson
Dec 19, 2002·Thyroid : Official Journal of the American Thyroid Association·Wilmar M Wiersinga, Luigi Bartalena
Jan 27, 2005·Thyroid : Official Journal of the American Thyroid Association·Gwenaëlle M Vidal-TrecanMark H Eckman
Feb 7, 2006·The Journal of Surgical Research·Chris M Schüssler-FiorenzaHerbert Chen
Feb 24, 2006·American Journal of Surgery·Kaare J WeberRichard A Prinz
Jun 1, 2006·Journal of the American College of Surgeons·Sebastien GaujouxFabrice Menegaux
Feb 24, 2007·Thyroid : Official Journal of the American Thyroid Association·Simon GrodskiLeigh W Delbridge
Mar 29, 2007·The Journal of Clinical Endocrinology and Metabolism·Yeşim ErbilSerdar Tezelman
Mar 11, 2008·World Journal of Surgery·Peter StålbergPer Hellman
Dec 17, 2008·Southern Medical Journal·Ugo IndraccoloPantaleo Greco
Mar 31, 2009·Endocrinology and Metabolism Clinics of North America·Laszlo Hegedüs
Jul 28, 2009·Journal of the American College of Surgeons·Haejin InJennifer E Rosen
Dec 25, 2009·World Journal of Surgery·Scott M Wilhelm, Christopher R McHenry
Mar 10, 2010·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·K SchererA J Bircher
Jun 21, 2011·American Journal of Surgery·Jeremy YipChung-Yau Lo
Dec 24, 2011·The British Journal of Oral & Maxillofacial Surgery·Leo H-H Cheng, Iain L Hutchison
Citations
May 19, 2007·The Veterinary Journal·Robert Sellers, John Gloster
Sep 9, 2017·Clinical Nursing Research·Semra Atasayar, Sevil Guler Demir
May 10, 2017·Endocrine·Y S HussainS P Balasubramanian
Dec 22, 2017·Primates; Journal of Primatology·Benoît QuintardKarin Lemberger
Dec 24, 2018·Journal of Clinical Medicine·Hyeong Won YuKyu Eun Lee
Jan 7, 2020·International Journal of Surgery Case Reports·Raja HusainTariq Madkhali