Gravitational venous drainage is significantly faster in patients with varicose veins

Phlebology
Christopher R LattimerE Mendoza

Abstract

It has been proposed that varicose veins may be caused by a degree of impeded proximal venous drainage (pelvic venous obstruction) in the same way that biological tubes dilate in response to an obstruction. The venous drainage index (VDI) of air-plethysmography (APG) was used to test this hypothesis. A dependency to elevation manoeuvre was used to provoke gravitational venous drainage. A rapid reduction in calf volume implied good drainage. This was a single centre, proof-of-concept study comparing gravitational venous drainage in varicose vein patients and controls. Leg filling and drainage manoeuvres (elevation to dependency and dependency to elevation) were performed three times per leg in 15 patients (7 male, 8 right) and 16 controls (3 male, 8 right). The VDI was measured in the same way the established venous filling index (VFI) is calculated to quantify filling: VDI = 90% of venous drainage volume (90VDV)/90% venous drainage time (VDT90). The patients were significantly older at 58 (41-75) years versus the controls 47 (18-58), p = 0.001. There was no significant difference between the groups in weight, height, BMI or common femoral vein diameter. The patients were (C2 = 8; C3 = 1, C4 = 6), VCSS 4 (1-11) with a median ref...Continue Reading

References

Nov 1, 1992·European Journal of Vascular Surgery·M LeonA N Nicolaides
Feb 1, 1989·The Journal of Dermatologic Surgery and Oncology·M P Goldman, A Fronek
Aug 1, 1989·Journal of Biomechanical Engineering·R D Kamm, T J Pedley
Jun 1, 1989·The British Journal of Surgery·H ClarkeA N Nicolaides
Jan 1, 1995·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·A Fronek
Dec 11, 1997·AJR. American Journal of Roentgenology·M M Abu-YousefT J Barloon
May 12, 1998·Journal of Vascular Surgery·E CriadoB A Keagy
Mar 10, 2000·Journal of Vascular Surgery·A FronekR Kim
Jun 8, 2000·Journal of Vascular Surgery·R B RutherfordG L Moneta
Jul 6, 2000·Journal of Vascular Surgery·M H MeissnerD E Strandness
Apr 11, 2001·Journal of Vascular Surgery·E KalodikiA N Nicolaides
Apr 5, 2002·Journal of Vascular Surgery·Peter Neglén, Seshadri Raju
Sep 1, 1963·Journal of Applied Physiology·S PERMUTT, R L RILEY
Nov 7, 2003·Journal of Vascular Surgery·Peter NeglénSeshadri Raju
Apr 28, 2004·Journal of Vascular Surgery·Melina R KibbeJon Matsumura
Dec 29, 2004·Journal of Vascular Surgery·Bo EklöfUNKNOWN American Venous Forum International Ad Hoc Committee for Revision of the CEAP Classification
Mar 11, 2008·American Journal of Physiology. Heart and Circulatory Physiology·Steven P DownieX Yun Xu
Mar 6, 2012·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·C R LattimerG Geroulakos
Dec 12, 2012·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·E MendozaF Amsler
Nov 26, 2013·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·C R LattimerG Geroulakos
Apr 4, 2015·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Ying-Sheng KuoYing-Chi Tseng
Jan 1, 2014·Journal of Vascular Surgery. Venous and Lymphatic Disorders·Seshadri RajuJake Olivier
Oct 1, 2014·Journal of Vascular Surgery. Venous and Lymphatic Disorders·Christopher R LattimerEvi Kalodiki

❮ Previous
Next ❯

Citations

May 11, 2016·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·C R LattimerG Geroulakos

❮ Previous
Next ❯

Software Mentioned

SPSS®

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.