Greater Frequency of Fruit and Vegetable Consumption Is Associated With Lower Prevalence of Peripheral Artery Disease

Arteriosclerosis, Thrombosis, and Vascular Biology
Sean P HeffronJeffrey S Berger

Abstract

Although fruit and vegetable (F&V) consumption is associated with lower risk of coronary heart disease and stroke, its association with peripheral artery disease (PAD) is less certain. We, thus, sought to characterize F&V intake and investigate the association between F&V consumption and presence of PAD in a large community sample. Self-referred participants at >20 000 US sites who completed medical and lifestyle questionnaires were evaluated by screening ankle brachial indices for PAD (ankle brachial index ≤0.9). Among 3 696 778 individuals, mean age was 64.1±10.2 years and 64.1% were female. Daily consumption of ≥3 servings of F&V was reported by 29.2%. Increasing age, female sex, white race, never smoking, being currently married, physical activity, increasing income, and frequent consumption of fish, nuts, and red meat were positively associated with daily consumption of F&V. After multivariable adjustment, there was a stepwise inverse association between F&V intake and PAD. Participants reporting daily intake of ≥3 servings of F&V had 18% lower odds of PAD than those reporting less than monthly consumption. In unadjusted and multivariable-adjusted models, the inverse association with F&V became stronger as ankle brachial i...Continue Reading

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Citations

Apr 27, 2018·Arteriosclerosis, Thrombosis, and Vascular Biology·Kimio Satoh, Hiroaki Shimokawa
Oct 17, 2018·European Heart Journal·Vincenzo LionettiGrant N Pierce
Nov 26, 2020·The American Journal of Clinical Nutrition·Nicola P BondonnoFrederik Dalgaard
Dec 29, 2020·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·Tatsuya ShirakiUNKNOWN SPINACH study investigators
Jul 3, 2021·Nutrients·Ahmed IsmaeelPanagiotis Koutakis

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