Green and ecofriendly synthesis of silver nanoparticles: Characterization, biocompatibility studies and gel formulation for treatment of infections in burns

Journal of Photochemistry and Photobiology. B, Biology
Kiran JadhavMrityunjaya Patil

Abstract

The current study summarizes a unique green process for the synthesis of silver nanoparticles (AgNPs) by simple treatment of silver nitrate with aqueous extract of Ammania baccifera. Phytosynthesized AgNPs were characterized by various advanced analytical methods and studied for its use against infections associated with burns. Formation of AgNPs was observed by visual color change from colorless to dark brown and confirmed by UV-visible characteristic peak at 436 nm. Zeta potential, particle size and polydispersity index of nano-silver were found to be -33.1 ± 1.12, 112.6 ± 6.8 nm and 0.3 ± 0.06 respectively. XRD spectra revealed crystalline nature of AgNPs whereas TEM confirmed the presence of mixed morphology of AgNPs. The overall approach designated in the present research investigation for the synthesis of AgNPs is based on all 12 principles of green chemistry, in which no man-made chemical other than the silver nitrate was used. Synthesized nano-silver colloidal dispersion was initially tested for minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) against a panel of organisms involved in infections associated with burns (Pseudomonas aeruginosa (PA), Staphylococcus aureus (SA) and methicill...Continue Reading

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Citations

Aug 20, 2016·Journal of Photochemistry and Photobiology. B, Biology·Palanivel SathishkumarThayumanavan Palvannan
Apr 19, 2017·Materials Science & Engineering. C, Materials for Biological Applications·Rajeshwari H RSuneel Dodamani
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Dec 13, 2017·Artificial Cells, Nanomedicine, and Biotechnology·Shaan Bibi Jaffri, Khuram Shahzad Ahmad
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Jan 17, 2020·Nanoscale·Katayoon KalantariThomas J Webster
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Oct 19, 2019·IET Nanobiotechnology·Debalina BhattacharyaMainak Mukhopadhyay
Nov 24, 2020·3 Biotech·Jaison JeevanandamMichael K Danquah
Apr 3, 2021·Journal of Controlled Release : Official Journal of the Controlled Release Society·Ying WeiXing Tang
Jan 19, 2021·ACS Biomaterials Science & Engineering·Satveer JagwaniRaghvendra Bohara
Mar 12, 2018·ACS Biomaterials Science & Engineering·Kiran JadhavRaghvendra Bohara

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