Green fabricated CuO nanobullets via Olea europaea leaf extract shows auspicious antimicrobial potential

IET Nanobiotechnology
Qaisar MaqboolNyla Jabeen

Abstract

In present investigation, copper oxide (CuO) nanostructures have been prepared via green chemistry. Olea europaea leaf extract act as strong chelating agent for tailoring physical as well as bio-medical characteristics of CuO at the nano-size. Physical characterisation such as scanning electron microscope analysis depicts the formation of homogenised spherical shape nanoparticles (NPs) with average size of 42 nm. X-ray diffraction and Fourier transform infrared spectroscopy further confirmed the crystalline pure phase and monoclinic structure. High performance liquid chromatography (HPLC) testing is performed to evaluate the relative concentration of bioactive molecules in the O. europaea leaf extract. From HPLC results capping action of organic molecules around CuO-NPs is hypothesised. The antimicrobial potency of biosynthesised CuO-NPs have been evaluated using colony forming unit (CFU) counting assay and disc diffusion method which shows a significant zone of inhibition against bacterial and fungal strains may be highly potential for future antimicrobial pharmaceutics. Furthermore, reduction of various precursors by plant extract will reduce environmental impact over chemical synthesis.

References

Jun 1, 1989·Physical Review. B, Condensed Matter·J LiK N Tu
Nov 24, 2001·Nature·A H MacDonald
Aug 9, 2002·Journal of Agricultural and Food Chemistry·Raffaella BrianteRoberto Nucci
Jan 31, 2006·Journal of Chromatography. a·R Japón-LujánM D Luque de Castro
Mar 15, 2006·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·M G SoniR Crea
Mar 24, 2007·Nanomedicine : Nanotechnology, Biology, and Medicine·Jun Sung KimMyung-Haing Cho
Feb 6, 2008·Acta Biomaterialia·Jayesh P RupareliaSuparna Mukherji
Apr 3, 2009·International Journal of Antimicrobial Agents·Douglas Roberto MonteiroDebora Barros Barbosa
Dec 24, 2010·Scientia pharmaceutica·Syed Haris Omar
Sep 27, 2012·Colloids and Surfaces. B, Biointerfaces·Dhaneswar DasSwapan Kumar Dolui
Mar 8, 2013·International Journal of Nanomedicine·Vinod Vellora Thekkae Padil, Miroslav Černík
Jan 15, 2016·IET Nanobiotechnology·Nattanmi Raman Dhineshbabu, Venkatachalam Rajendran
Oct 28, 2016·International Journal of Nanomedicine·Qaisar MaqboolTariq Jan
Nov 21, 2013·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Abdulrahman Syedahamed Haja HameedGanesan Ravi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.