Green techniques in comparison to conventional ones in the extraction of Amaryllidaceae alkaloids: Best solvents selection and parameters optimization

Journal of Chromatography. a
Sarah S TaklaFikria A Darwish

Abstract

An undisputed trend in sample preparation at present is to meet the requirements of green chemistry especially in the field of natural products. Green technology continuously pursues new solvents to replace common organic solvents that possess inherent toxicity. Over the past two decades, non-ionic surfactants have gained enormous attention from the scientific community. The micelle-mediated extraction and cloud-point preconcentration (CPE) methods offer a convenient alternative to the conventional extraction systems. Recently, natural deep eutectic solvents (NDESs) have emerged as green and sustainable solvents for efficient extraction of bioactive compounds or drugs. They are generally composed of neutral, acidic or basic compounds that form liquids of high viscosity when mixed in certain molar ratio. The presented work aimed to comprehensively compare and evaluate the potential and effectiveness of NDES as well as non-ionic surfactants (Genapol X-080, Triton X-100 and Triton X-114) for extraction of Amaryllidaceae alkaloids from Crinum powellii bulbs as representative example of plant material, in comparison to the conventional solvents (methanol, ethanol and water).A new validated high-performance thin-layer chromatographic...Continue Reading

Citations

Sep 25, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Radu Claudiu FierascuIrina Fierascu
Sep 22, 2020·Critical Reviews in Analytical Chemistry·Sing Chuong ChuoAbdullah Alarifi
Jan 23, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Ilaria ChiocchioFerruccio Poli
Jul 25, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Ekaterina D ObluchinskayaAlexander N Shikov

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