Green urine in a critically ill patient

American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation
Gerardo Carpenito, Ira Kurtz

Abstract

The development of discolored urine in the critically ill patient, although uncommon, may have many possible causes, with the most likely source related to medication administration. Studies were undertaken in a 39-year-old man who developed dark green urine while in the intensive care unit for neutropenic sepsis. Although the patient had developed prior nonoliguric renal failure stemming from his sepsis, his renal function at the time of presentation of urine discoloration was considered normal. Review of his medications and intravenous infusions suggested the most likely cause was the food dye placed in his enteral tube feedings. Spectrophotometric evaluation of the urine confirmed the presence of Food Dye and Color Blue Number 1 (FD&C Blue No. 1). This case shows that significant gastrointestinal absorption of FD&C Blue No. 1 can occur. FD&C Blue No. 1 should be considered in the differential diagnosis of dark green discolored urine.

References

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Citations

Feb 8, 2006·Postgraduate Medical Journal·C L Foot, J F Fraser
Mar 3, 2009·Journal of Neurology·Andreas HufschmidtI Peschen
Feb 11, 2004·Chest·Maria R LucarelliElliott D Crouser
Jul 29, 2011·Nephrology·Stalin Viswanathan, Augustine John
Mar 20, 2016·Dysphagia·Stevie MarvinSusan Thibeault
Apr 23, 2016·Journal of Evidence-based Complementary & Alternative Medicine·Sepideh KolouriVahid Tafazoli
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Dec 23, 2011·Southern Medical Journal·Ryan D Aycock, Dara A Kass
Feb 28, 2019·Journal of Epilepsy Research·Da Eun LeePamela Song

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