Green, yellow and red emitting CdTe QDs decreased the affinities of apigenin and luteolin for human serum albumin in vitro

Journal of Hazardous Materials
Jianbo XiaoYalong Bai

Abstract

Apigenin and luteolin were studied for the affinities for human serum albumin (HSA) in the presence and absence of three CdTe QDs with different sizes. The fluorescence intensities of HSA decreased remarkably with increasing concentration of QDs. Apigenin and luteolin resulted in obvious blue-shifts of the lambda(em) of HSA from 340 nm to 330 nm and 320 nm. However, the extents of blue-shifts induced by apigenin or luteolin in the presence of QDs were much smaller than that in the absence of QDs. The quenching process of apigenin for HSA was easily affected by the QDs size than that of luteolin. QDs decreased the quenching constant from 37.23% to 52.38% for apigenin. However, QDs decreased the quenching constant from 56.18% to 60.38% for luteolin. QDs decreased the affinity of apigenin or luteolin for HSA. G-QDs, Y-QDs, and R-QDs decreased the affinity of apigenin for HSA about 14.71%, 12.65% and 6.91%. The binding affinity of apigenin for HSA increased with increasing QDs size. However, the binding affinity of luteolin for HSA decreased with increasing QDs size. G-QDs, Y-QDs, and R-QDs decreased the affinities of luteolin for HSA about 19.48%, 22.47% and 28.18%.

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Citations

Aug 26, 2011·Journal of Agricultural and Food Chemistry·Jianbo XiaoKoichiro Yamamoto
Dec 31, 2011·Journal of Agricultural and Food Chemistry·Xi-Min ZhouXing-Guo Chen
Jul 17, 2012·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·Lu LaiYi Liu
Aug 30, 2011·Journal of Hazardous Materials·Jiahan LiYi Liu
May 11, 2011·Nanotoxicology·Jianbo XiaoXiaoqing Chen
Sep 3, 2017·Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry·Zizhen LiXudong Cao
Jan 31, 2012·Integrative Biology : Quantitative Biosciences From Nano to Macro·Xiaoling Ni
Jun 20, 2014·Physical Chemistry Chemical Physics : PCCP·Supriya Saha, Pranab Sarkar
Sep 15, 2012·Organic & Biomolecular Chemistry·Ximin ZhouXingguo Chen
Mar 5, 2021·International Journal of Biological Macromolecules·Wen GaoHuijun Dong
Apr 24, 2016·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·Ricardo Q AucelioAndrea R da Silva

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