Grooved and nongrooved clear corneal incisions in phacoemulsification: permeability study

European Journal of Ophthalmology
Victor D BergamascoGustavo R Malavazzi

Abstract

To detect the inflow of trypan blue through grooved and nongrooved sutureless self-sealing clear corneal incisions at the end of phacoemulsification as compared to a control group. A prospective randomized masked trial considered 52 eyes randomized into 3 groups in which phacoemulsification was performed: group A, nongrooved incisions; group B, grooved incisions; and group C, controls. By the end of each surgery, trypan blue was instilled on the ocular surface in groups A and B and rinsed out after 2 minutes. A sample of the anterior chamber content was collected and analyzed by high-performance liquid chromatography to identify and quantify the trypan blue concentration. The presence of trypan blue was expressed as a specific single peak graphic image. The mean areas of these peaks were used to assess the groups using a nonparametric Mann-Whitney test. There was a statistically significant difference between the nongrooved incisions group and the control group (p = 0.0448). No significant difference was observed between group B (grooved incision) and controls (p = 0.1800). Trypan blue was detected in the anterior chamber when nongrooved clear corneal incision was used. There was no trypan blue detection in the group with groov...Continue Reading

References

Jan 1, 1994·Journal of Cataract and Refractive Surgery·D W Langerman
Jan 8, 1993·Current Opinion in Ophthalmology·P J Agapitos
May 31, 2002·Journal of Cataract and Refractive Surgery·Huseyin YetikSehirbay Ozkan
Jul 31, 2003·American Journal of Ophthalmology·Blake A CooperPaul A Thompson
Dec 4, 2003·Ophthalmology·Peter J McDonnellZhongping Chen
Mar 19, 2004·Survey of Ophthalmology·Mehran TabanPeter J McDonnell
Aug 4, 2004·American Journal of Ophthalmology·Melvin A SaraybaPeter J McDonnell
May 11, 2005·Archives of Ophthalmology·Mehran TabanPeter J McDonnell
May 11, 2005·Archives of Ophthalmology·Mehran TabanPeter J McDonnell
May 16, 2006·Journal of Cataract and Refractive Surgery·Satish Chawdhary, Aashish Anand
Dec 27, 2006·Journal of Cataract and Refractive Surgery·I Howard FineMark Packer
Feb 27, 2007·Journal of Cataract and Refractive Surgery·Samuel Masket, Shaleen Belani
Jul 29, 2008·Journal of Cataract and Refractive Surgery·Jonathan Etter, Terry Kim
Mar 3, 2009·Journal of Cataract and Refractive Surgery·Sylvère Dupont-MonodChristophe Baudouin

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