Group A streptococcal genotypes from pediatric throat isolates in Rome, Italy

Journal of Clinical Microbiology
G DicuonzoB Beall

Abstract

In a study assessing genetic diversity, 114 group A streptococcus (GAS) isolates were recovered from pediatric pharyngitis patients in Rome, Italy. These isolates comprised 22 different M protein gene (emm) sequence types, 14 of which were associated with a distinct serum opacity factor/fibronectin binding protein gene (sof) sequence type. Isolates with the same emm gene sequence type generally shared a highly conserved chromosomal macrorestriction profile. In three instances, isolates with dissimilar macrorestriction profiles had identical emm types; in each of these cases multilocus sequence typing revealed that isolates with the same emm type were clones having the same allelic profiles. Ninety-eight percent of the pharyngeal isolates had emm types previously found to be highly associated with mga locus gene patterns commonly found in pharyngeal GAS isolates.

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Citations

Dec 4, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Richard F FacklamBernard Beall
Aug 13, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Stanford T ShulmanUNKNOWN US Streptococcal Pharyngitis Surveillance Group
Dec 4, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Robert R TanzUNKNOWN North American Streptococcal Pharyngitis Surveillance Group
Dec 24, 2005·The Pediatric Infectious Disease Journal·Preeti JaggiStanford T Shulman
Nov 19, 2002·Antimicrobial Agents and Chemotherapy·Giordano DicuonzoBernard Beall
Oct 10, 2006·Journal of Bacteriology·Zerina KratovacDebra E Bessen
Oct 9, 2003·Journal of Clinical Microbiology·Allon E MosesRan Nir-Paz
Jun 7, 2003·Journal of Clinical Microbiology·Sebastián AlbertíUNKNOWN Spanish Surviellance Group for Respiratory Pathogens
Mar 8, 2005·Journal of Clinical Microbiology·Sebastián AlbertíUNKNOWN Spanish Surveillance Group for Respiratory Pathogens
Aug 6, 2005·Journal of Clinical Microbiology·Nicole M GreenJames M Musser
Sep 8, 2005·Journal of Clinical Microbiology·Wezenet Tewodros, Göran Kronvall
Apr 1, 2010·Future Microbiology·Debra E Bessen, Sergio Lizano
Jul 1, 2008·Microbial Pathogenesis·Feng LuoDebra E Bessen
Jun 11, 2004·Letters in Applied Microbiology·V SagarA Chakraborti
Jan 9, 2004·Clinics in Laboratory Medicine·Paul D Fey, Mark E Rupp
Dec 3, 2014·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Debra E BessenHervé Tettelin
Dec 25, 2007·The Korean journal of laboratory medicine·Eun Ha Koh, Sunjoo Kim
Dec 15, 2006·International Journal of Immunopathology and Pharmacology·I SantinoM Del Piano
Mar 8, 2003·Journal of Clinical Microbiology·Claudia ZampaloniSandro Ripa
Jan 31, 2006·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·G LorinoG Dicuonzo

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