Group and individual regulation of physiology and behavior: a behavioral, thermographic, and acoustic study of mouse development.

Physiology & Behavior
Christopher Harshaw, J R Alberts

Abstract

The traditional approach to the study of thermoregulation in young animals focuses on the regulatory capacities of individuals, which, for multiparous species, risks ignoring critical aspects of the early developmental niche. Here, we examined the ontogeny of regulatory behavior in C57BL/6 mice, employing simultaneous behavioral, thermographic, and acoustic measures of groups and individual pups. Litters of mice were placed in a chamber on Postnatal Day (PND) 2, 4, or 8, in which the ambient temperature (T(a)) gradually cycled (over 50 min) from warm (36.5°C) to cool (20°C) and back (to 36.5°C). Litters of all three ages displayed "group regulatory behavior," whereby group size varied with changes in T(a). This coupling, moreover, improved with age. Infrared thermography was used to monitor skin temperature of pups' interscapular (T(IS)) and rump (T(rump)) areas, and to estimate brown adipose tissue (BAT) thermogenesis (T(IS)-T(rump)) in PND4 and PND8 individuals and huddles. Huddling was found to significantly reduce heat loss in pups subject to thermal challenge as groups, compared to pups challenged as individuals. Additionally, females were found to display significantly warmer T(IS) and T(rump) values than male huddlemates...Continue Reading

References

Jan 1, 1975·Comparative Biochemistry and Physiology. A, Comparative Physiology·D M Bryant, C J Hails
May 1, 1975·Comparative Biochemistry and Physiology. A, Comparative Physiology·M W Stanier
Apr 1, 1978·Journal of Comparative and Physiological Psychology·J R Alberts
Apr 1, 1978·Journal of Comparative and Physiological Psychology·J R Alberts
Sep 1, 1978·Developmental Psychobiology·M A Hofer, H Shair
May 1, 1990·Physiology & Behavior·C J Gordon
Oct 1, 1990·Behavioral Neuroscience·M S Blumberg, J R Alberts
Jan 1, 1988·Pharmacology, Biochemistry, and Behavior·P Huttunen, M L Kortelainen
Sep 1, 1987·Developmental Psychobiology·M J West, A P King
Sep 1, 1974·Behavioral Biology·W P SmothermanT A Zachman
Jul 25, 1970·Nature·G D Sewell
Jul 1, 1983·Physiology & Behavior·P BatchelderC B Lynch
Mar 1, 1993·Behavioral and Neural Biology·J Rankin, A Manning
Dec 17, 1997·Journal of Theoretical Biology·J C Schank, J R Alberts
Apr 29, 1998·Developmental Psychobiology·R F Kirby, M S Blumberg
Aug 26, 1998·Pflügers Archiv : European journal of physiology·S QuevedoA Palou
Jun 21, 2001·Proceedings. Biological Sciences·J C Schank, J R Alberts
Sep 25, 2001·Developmental Psychobiology·G Sokoloff, M S Blumberg
Nov 26, 2002·Trends in Genetics : TIG·Eunju SeongMargit Burmeister
Dec 12, 2002·Cellular and Molecular Life Sciences : CMLS·A M RodriguezA Palou
Nov 1, 1960·The Journal of Physiology·P M TAYLOR
Jan 13, 2004·Physiological Reviews·Barbara Cannon, Jan Nedergaard
Feb 13, 2004·Genes, Brain, and Behavior·J M LongA Wynshaw-Boris
Mar 8, 2005·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·Crystal L MurciaKarl Herrup
Dec 23, 2006·Developmental Psychobiology·Jeffrey R Alberts
May 29, 2007·Neuroscience Letters·Bieke BollenJorge Gallego
Nov 20, 2008·Genes, Brain, and Behavior·S S MoyJ M Lauder
Dec 24, 2010·The Journal of Experimental Biology·Barbara Cannon, Jan Nedergaard

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Citations

May 15, 2016·Psychoneuroendocrinology·Silja McIlwrickChadi Touma
Dec 5, 2015·Scientific Reports·Stefanie F MaurerMartin Klingenspor
Jun 19, 2019·Developmental Psychobiology·Aurélie VerjatChristophe Féron
Apr 17, 2015·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Rebecca L MaherSteven J Swoap
Apr 22, 2015·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Agnieszka Chabowska-KitaLeslie P Kozak
Nov 21, 2017·Developmental Psychobiology·Delia S Shelton, Jeffrey R Alberts
May 26, 2018·Scientific Reports·Sophie St-CyrPatrick O McGowan
Jan 8, 2019·Particle and Fibre Toxicology·Keith Morris-SchafferDeborah A Cory-Slechta
May 8, 2021·Royal Society Open Science·Julia D KozhevnikovaElena V Volodina

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