Abstract
The objective was to determine the frequency and risk factors of anogenital colonization by Streptococcus agalactiae (GBS) in pregnant women infected with human immunodeficiency virus type 1 (HIV-1). A prospective study was conducted on 207 pregnant women divided into two groups: HIV group (n=101) and a control group consisting of HIV-uninfected pregnant women (n=106) to assess regional colonization by GBS. Anal and vaginal swabs were collected and cultured in Todd-Hewitt broth, followed by a confirmatory test. For a control group with an anticipated proportion based on literature research of 10-30% and alpha=0.05, a sample size of 100 would have a power of 80% to detect a difference of 15% or greater with a study group. The mothers were studied in terms of frequency of anogenital colonization by GBS, maternal epidemiological data, and TCD4 lymphocyte counts. The results were analyzed using the chi(2)-test, Fisher's exact test and the Student's t-test, with the level of significance set at p<0.05. Twenty (19.8%) HIV-1-infected pregnant women were found to be colonized by GBS at between 35 and 37 weeks' gestation. In the control group, the prevalence of GBS was 14.1%. No significant increase in GBS colonization was observed in H...Continue Reading
References
Mar 1, 1977·The Journal of Infectious Diseases·C J BakerW M McCormack
Nov 1, 1990·The Pediatric Infectious Disease Journal·I M GladstoneR S Baltimore
Jun 26, 1986·The New England Journal of Medicine·K M Boyer, S P Gotoff
Dec 1, 1973·The Journal of Pediatrics·C J Baker, F F Barrett
Nov 1, 1983·The Journal of Infectious Diseases·K M BoyerS P Gotoff
Jan 1, 1981·Scandinavian Journal of Infectious Diseases·K PerssonA Forsgren
Jun 1, 1981·The Journal of Infectious Diseases·B F AnthonyC J Hobel
Feb 1, 1995·Diagnostic Microbiology and Infectious Disease·M W PlattL J Nims
Feb 1, 1994·British Journal of Obstetrics and Gynaecology·H McKenzieD T Benvie
Jul 1, 1995·Diagnostic Microbiology and Infectious Disease·R M Ostroff, J W Steaffens
Feb 1, 1997·Obstetrics and Gynecology·E RamosD Briones
Dec 5, 1998·Obstetrics and Gynecology·B J CrispW F Nauschuetz
Sep 1, 1999·The Journal of Obstetrics and Gynaecology Research·T YamamotoY Kuwabara
Oct 17, 2002·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Erik HonigWillem I van der Meijden
Mar 19, 2004·Revista do Hospital das Clínicas·Patrícia El BeituneErnesto Antônio Figueiró-Filho
Apr 28, 2004·Infectious Diseases in Obstetrics and Gynecology·David S McKennaIke Northern
Jul 20, 2004·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·F J Picard, M G Bergeron
Jul 24, 2004·Expert Review of Vaccines·G L Gilbert
Aug 6, 2004·The Journal of Infectious Diseases·Feng-Ying C LinJohn D Clemens
Citations
Feb 22, 2007·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Patrícia El BeituneCarol Kobori Da Fonseca
Oct 21, 2011·Journal of Women's Health·Melisa ShahDeborah Cohan
Jun 24, 2010·Clinics in Perinatology·Jennifer R Verani, Stephanie J Schrag
Mar 2, 2010·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Rooyen Tinago MavenyengwaSvein Arne Nordbø
Mar 9, 2007·Gynécologie, obstétrique & fertilité·M JerbiH Khairi
Jan 2, 2007·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·P El BeituneC M L Maffei
Feb 6, 2015·The Journal of Infectious Diseases·Ziyaad DangorShabir A Madhi
Dec 25, 2012·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Esaú JoaoUNKNOWN NISDI/LILAC Protocol
May 30, 2016·The Lancet Infectious Diseases·Gaurav KwatraShabir A Madhi
Mar 18, 2017·Journal of Neonatal-perinatal Medicine·R Biobaku OluwafunmilolaO Imaralu John
Jun 16, 2011·Scandinavian Journal of Infectious Diseases·Esau C JoaoBeatriz Gilda J Grinsztejn
Nov 30, 2019·BMC Infectious Diseases·Szilvia KardosOrsolya Dobay
Oct 25, 2017·Scientific Reports·Piet CoolsMario Vaneechoutte
Dec 3, 2016·Frontiers in Immunology·Nicolas DaubyTessa Goetghebuer