Abstract
Gait abnormalities and vascular disease risk factors are associated with cognitive impairment in aging. To determine the impact of group-based exercise and dual-task training on gait and vascular health, in active community-dwelling older adults without dementia. Participants [n=44, mean (SD) age: 73.5 (7.2) years, 68% female] were randomized to either intervention (exercise+dual-task; EDT) or control (exercise only; EO). Each week, for 26 weeks, both groups accumulated 50 or 75 min of aerobic exercise from group-based classes and 45 min of beginner-level square stepping exercise (SSE). Participants accumulating only 50 min of aerobic exercise were instructed to participate in an additional 25 min each week outside of class. The EDT group also answered cognitively challenging questions while performing SSE (i.e., dual-task training). The effect of the interventions on gait and vascular health was compared between groups using linear mixed effects models. At 26 weeks, the EDT group demonstrated increased dual-task (DT) gait velocity [difference between groups in mean change from baseline (95% CI): 0.29 m/s (0.16-0.43), p<0.001], DT step length [5.72 cm (2.19-9.24), p =0.002], and carotid intima-media thickness [0.10mm (0.003-0.2...Continue Reading
References
Oct 7, 1997·Circulation·M L BotsD E Grobbee
Jan 8, 1999·The New England Journal of Medicine·D H O'LearyS K Wolfson
Feb 9, 2005·Circulation·Thomas G PickeringEdward J Roccella
May 17, 2005·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Jun SugawaraIchiro Kono
May 17, 2006·Psychological Research·Eric RuthruffRoger Remington
Jun 29, 2006·Aging Clinical and Experimental Research·Ryosuke Shigematsu, Tomohiro Okura
Nov 29, 2007·Neuroepidemiology·Caterina RosanoAnne B Newman
Jun 28, 2008·Journal of Applied Physiology·Douglas R SealsHirofumi Tanaka
Dec 9, 2008·Archives of Physical Medicine and Rehabilitation·Jennifer S BrachAnne B Newman
Dec 23, 2008·Diabetes Research and Clinical Practice·Kunihiko AizawaRobert J Petrella
Jun 19, 2009·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Ihab HajjarLewis A Lipsitz
May 21, 2010·BMC Geriatrics·Teresa Liu-AmbroseKarim M Khan
Dec 14, 2011·Clinical Science·Dick H J ThijssenDaniel J Green
Nov 29, 2012·European Heart Journal·Lian EngelenUNKNOWN Reference Values for Arterial Measurements Collaboration
Feb 14, 2013·Journal of the Royal Army Medical Corps·M J World
May 1, 2013·Current Alzheimer Research·Rufus O AkinyemiRaj N Kalaria
Aug 13, 2013·Neurology·Connie W TsaoGary F Mitchell
Sep 24, 2013·BMC Neuroscience·Nathan TheillLutz Jäncke
Jan 30, 2014·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Qu TianCaterina Rosano
Apr 1, 2014·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Bartomeu ColomFrancisco J Garcia-Palmer
Jul 18, 2014·Lancet Neurology·Sam NortonCarol Brayne
Sep 4, 2014·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Manuel Montero-OdassoSusan W Muir-Hunter
Sep 10, 2014·Journal of Neurologic Physical Therapy : JNPT·Moran DorfmanAnat Mirelman
Nov 21, 2014·Medicine and Science in Sports and Exercise·Ramzy RossJason M R Gill
Mar 31, 2015·Alzheimer's Research & Therapy·Kenneth M Langa
Citations
Apr 4, 2017·Frontiers in Human Neuroscience·Tony J SzturmMayur Nankar
Dec 26, 2017·European Review of Aging and Physical Activity : Official Journal of the European Group for Research Into Elderly and Physical Activity·Oron LevinGal Ziv
May 16, 2018·Gerontology & Geriatric Medicine·Narlon C Boa Sorte SilvaRobert J Petrella
Mar 18, 2017·Journal of Alzheimer's Disease : JAD·Michael A GregoryRobert J Petrella
Dec 4, 2020·Journal of Aging and Physical Activity·Valéria Mayaly Alves de OliveiraRodrigo Cappato de Araújo
Jan 1, 2021·BMJ Open·Rosalinda Sánchez-ArenasRyosuke Shigematsu
Jul 1, 2021·Journal of Aging Research·Neildja Maria da SilvaNúbia Maria Freire Vieira Lima