PMID: 8950333Jan 1, 1997Paper

Growth and growth hormone secretion after treatment for childhood non-Hodgkin's lymphoma

Medical and Pediatric Oncology
B O SamuelssonK Albertsson-Wikland

Abstract

The aim of this study was to evaluate the growth and growth hormone (GH) secretion, as assessed by the rate and pattern of secretion, in patients in remission from non-Hodgkin's lymphoma (NHL) who had been treated with corticosteroids and intense chemotherapy. None of the patients had received cranial irradiation. Twelve children were investigated yearly by taking 24-hour GH profiles starting 1 year from the time of diagnosis. The mean age at onset of the disease was 7.5 years. Another 12 young adults were studied in a cross-sectional manner 4.1-21.3 years (mean, 9.0 years) after diagnosis of NHL. The mean age at onset of the disease was 10.7 years. The median height velocity was significantly decreased during the 1st year following diagnosis (standard deviation scores [SDS] -0.15, P < .001), especially during the first 3 months (SDS -0.75, P < .001) when the most intense treatment was given. During the 2nd year height velocity was still somewhat reduced (SDS -0.13, P < .001). However, there was no reduction in final attained height. Spontaneous GH secretion, in terms of both secretory rate and pulsatile pattern, was evaluated by measuring integrated GH concentrations in 20-minute blood samples collected over a 24-hour period. ...Continue Reading

References

Dec 13, 1975·Lancet·C Dacou-VoutetakisL Zannos-Mariolea
Feb 1, 1992·Acta Endocrinologica·K Albertsson-Wikland, S Rosberg
Feb 1, 1989·Archives of Disease in Childhood·C MoëllK Albertsson-Wikland
Feb 27, 1988·Lancet·P E ClaytonD A Price
Jan 1, 1988·Hormone Research·C MoëllK Albertsson-Wikland
Mar 1, 1986·Acta paediatrica Scandinavica·S R AhmedC G Beardwell
May 1, 1985·Acta paediatrica Scandinavica·S M HerberR D Milner
Dec 1, 1969·The Journal of Pediatrics·C R Sunderman, H A Pearson
Aug 1, 1980·Archives of Disease in Childhood·N K Griffin, J Wadsworth
Dec 1, 1994·Acta Paediatrica. Supplement·J KarlbergK Albertsson-Wikland
Jun 1, 1994·Archives of Disease in Childhood·H A DaviesS M Shalet

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Citations

Sep 18, 1999·Archives of Disease in Childhood·H Robson
Sep 8, 2011·Human Reproduction Update·W van DorpM M van den Heuvel-Eibrink
Aug 23, 2006·Leukemia & Lymphoma·Aynur OğuzSeçil Ozkan
Aug 5, 2006·Journal of Cellular Biochemistry·Cory J XianBruce K Foster
Sep 28, 2000·Cancer Treatment Reviews·B L van LeeuwenH J Hoekstra

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