Growth and maturation in the patients with congenital hypothyroidism detected by the neonatal screening program in Catalonia, Spain (1986-1997)

Medicina clínica
Anna Gibert AgullóNeus Potau Vilalta

Abstract

Many countries have developed screening programs for CH that bring about a normal somatic and psychological development. The aim of this study is to evaluate the evolution of cases detected by the screening program of congenital hypothyroidism in Catalonia. The was a descriptive, longitudinal study of a series of 136 cases of congenital hypothyroidism detected by the screening program in Catalonia from 1986 to 1997 and who had been checked in the Maternal-infantile Vall d'Hebron Hospital in Barcelona. Follow-up was carried out for growth and a psychological exploration was performed (McCarthy test and WISC-R). Males (30 cases, 22.1%) and females (106 cases, 77.9%) with congenital hypothyroidism of this study had a height, weight and BMI that were not different from those of the current population of Barcelona. Height was 0.5 SD above the Tanner reference values of 1966 and BMI was one SD above the Roland-Cachera reference values of 1982. This secular acceleration of growth has been observed in all developed countries. In a sample of 37.5% of the cases, psychological development did not differ from that of the reference population. However, a greater intensity of neonatal hypothyroidism and its most delayed normalization correla...Continue Reading

References

Aug 8, 1996·The New England Journal of Medicine·T ShenY Chang
May 1, 1997·Acta Paediatrica·S HeyerdahlA Larsson
Aug 14, 1999·Thyroid : Official Journal of the American Thyroid Association·J F Rovet
Mar 10, 2000·Pediatric Research·A M FredriksJ M Wit
Aug 31, 2002·American Journal of Human Biology : the Official Journal of the Human Biology Council·Angela M ThompsonDonald A Bailey
Jul 10, 2003·Annals of Human Biology·C Padez

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Citations

Dec 17, 2009·Medicina clínica·Ana M Fullana Montoro, Carmen Barona Vilar

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