Growth and metabolism of human tumor kidney cells on galactose and glucose.

Cytotechnology
A WagnerA Einsele

Abstract

The culture kinetics of human tumor kidney cells (TCL 598) grown on microcarriers are compared with media initially supplemented with either glucose alone or a mixture of galactose and glucose. Growth rates and maximal cell densities are similar, but cellular death is much slower in galactose than in glucose. Galactose is metabolized at a much slower specific rate than glucose. Cells grown in the galactose medium show a different pattern of lactate and pyruvate metabolism compared to cells grown in the glucose medium. Growth with galactose also favours oxidation of glutamine to alanine.

Citations

Jan 1, 1994·In Vitro Cellular & Developmental Biology. Animal·R D Griner, R G Schnellmann
Feb 18, 2011·Biotechnology and Bioengineering·Matthew GagnonDenis Drapeau
Jul 22, 2018·The Journal of Immunology : Official Journal of the American Association of Immunologists·Beata M ZygmuntCarlos A Guzmán
Sep 1, 1991·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·D B Craig
Apr 9, 2011·The American Journal of Chinese Medicine·Ebtesam A Al-SuhaimiReham A Al-Essa
Apr 5, 2021·Mitochondrion·Michèle J C de KokSylvia E Le Dévédec

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