Growth and nutritional status in children and adolescents with cystic fibrosis

Annals of Human Biology
Wioleta Umławska, Charles Susanne

Abstract

Growth retardation, delayed puberty and malnutrition are frequently observed in children suffering from cystic fibrosis. The aim of this study was to estimate growth and nutritional status in children with cystic fibrosis on the basis of body proportions and body mass index. Anthropometric data were collected from the medical histories of 62 patients treated in three cystic fibrosis treatment centers in Poland. Anthropometric parameters were expressed in terms of standard deviations away from age-specific and sex-specific reference means reported for the population of Poland. Two-way analysis of variance was used to determine whether the type of cystic fibrosis transmembrane conductance regulator (CFTR) mutation is correlated with age at the time of diagnosis and with body proportions. The type of mutation was significantly correlated with height, weight and transverse chest width. Growth retardation was greater in subjects diagnosed before they were 3 years old than in subjects diagnosed later. The children had infantile body proportions. Their legs were short and their trunks were long in comparison to their height. Almost 40% of the subjects suffered from malnourishment. Further study is needed to determine how growth in chi...Continue Reading

References

May 1, 1992·Archives of Disease in Childhood·J K WalesL S Taitz
Mar 1, 1984·Acta paediatrica Scandinavica·L MartinezD B Grant
May 1, 1994·Annals of Human Biology·P J Byard
Mar 1, 1994·European Journal of Pediatrics·G HaeuslerM Götz
Mar 13, 1999·The American Journal of Clinical Nutrition·H C LaiP M Farrell
Aug 18, 1999·Archives of Disease in Childhood·C E CollinsR L Henry
Apr 26, 2001·Journal of the American Dietetic Association·L T BekerR J Fink
Nov 20, 2001·The Journal of Pediatrics·J C Bucuvalas, S D Chernausek
May 15, 2002·The Journal of Pediatrics·Ross Shepherd
Oct 7, 2004·Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society·Scott C Bell, Ross W Shepherd
Mar 10, 2005·The Journal of Pediatrics·Carla Colombo, Alberto Battezzati
Sep 27, 2005·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Virginia A StallingsBabette S Zemel
Apr 8, 2006·Fertility and Sterility·Assimina Galli-TsinopoulouSanda Nousia-Arvanitakis

❮ Previous
Next ❯

Citations

Nov 9, 2012·The American Journal of Clinical Nutrition·Gia M BradleyGarry R Cutting
Dec 23, 2014·The Lancet. Respiratory Medicine·Katherine B Frayman, Susan M Sawyer
Aug 3, 2010·Folia Histochemica Et Cytobiologica·Wioleta UmławskaAnna Zielińska
Sep 25, 2008·Current Opinion in Pulmonary Medicine

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

JPEN. Journal of Parenteral and Enteral Nutrition
Julia L Matel
Current Opinion in Pulmonary Medicine
Michael S Schechter
The Cochrane Database of Systematic Reviews
Kevin W SouthernA D Nagelkerke
Journal of Pediatric Gastroenterology and Nutrition
Jacqueline R CohenVirginia A Stallings
© 2022 Meta ULC. All rights reserved