Growth, development and incidence of deformities in amphibian larvae exposed as embryos to naphthenic acid concentrations detected in the Canadian oil sands region

Environmental Pollution
Steven D Melvin, Vance L Trudeau

Abstract

Naphthenic acids (NA) have been identified as harmful environmental contaminants that influence survival, growth and development of wildlife. Amphibian larvae are particularly susceptible to waterborne contaminants, but little information exists regarding exposure of amphibian embryos or tadpoles to NA. Our results demonstrate that embryos of Lithobates pipiens and Silurana tropicalis exposed to 2-4 mg/l of a commercial NA blend suffer significant reductions (32% and 25%, respectively) in growth and development upon hatching. Increased incidences of deformities were observed in exposed individuals of both species, but were only significant in L. pipiens. Embryos suffered 100% mortality following exposure to 6 mg/l NAs, and narcosis at lower concentrations. LC50 estimates were 4.10 mg/l for 72-h exposure in L. pipiens and 4.13, 3.51, and 2.95 mg/l for 24-, 48-, and 72-h exposure in S. tropicalis. These data suggest that exposure to NAs at environmentally realized concentrations may negatively affect tadpole populations.

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Citations

Feb 28, 2013·Reproductive Biology and Endocrinology : RB&E·Vance L TrudeauLisa Taylor
Oct 4, 2014·Rapid Communications in Mass Spectrometry : RCM·S J RowlandL M Hewitt
Oct 19, 2016·Environmental Toxicology·Jie WangXiaoyan Tang
Sep 19, 2015·Journal of Toxicology and Environmental Health. Part a·Maria VuVance L Trudeau
Mar 8, 2013·Environmental Pollution·Steven D MelvinVance L Trudeau
Nov 2, 2016·Environmental Toxicology and Chemistry·Nikolas C ZetouniJonathan W Martin
May 20, 2017·Environmental Science & Technology·Megan ReichertKeith B Tierney
Nov 19, 2019·Journal of Applied Toxicology : JAT·Sarah D YoungStacey A Robinson
Jun 4, 2019·Frontiers in Endocrinology·Anita A ThambirajahCaren C Helbing
Apr 28, 2020·Toxicology in Vitro : an International Journal Published in Association with BIBRA·Nicole A I PhillipsJames L Stafford
Dec 24, 2018·The Science of the Total Environment·Denby McDonnellValerie S Langlois
Jun 26, 2018·The Science of the Total Environment·Jason M E AhadMartine M Savard

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