Growth factors in the eye

Progress in Growth Factor Research
J W McAvoy, C G Chamberlain

Abstract

In this review we report the distribution and functional significance of growth factors in the eye. Representatives of the major growth factor families are found in the eye: fibroblast growth factor, insulin and insulin-like growth factor, transforming growth factor-beta, platelet-derived growth factor, nerve growth factor, epidermal growth factor and colony-stimulating factor. There are numerous examples of their actions on ocular tissues in vitro and in some cases in vivo. The findings presented clearly illustrate that a growth factor can elicit different responses depending on the context of its action; the cell type involved, the concentration of the growth factor and the presence or absence of other growth factors can all influence the cellular response both quantitatively and qualitatively. The results of these studies in the eye are of general significance to our understanding of the role of growth factors in biological processes.

References

Jun 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·A B RobertsJ H Kehrl
Jan 1, 1986·Advances in Clinical Chemistry·R C Baxter
Aug 1, 1988·Trends in Neurosciences·Y A Barde
Jan 1, 1989·Progress in Growth Factor Research·M Klagsbrun
Jul 1, 1989·The Journal of Cell Biology·D B Rifkin, D Moscatelli
Jan 1, 1989·Annual Review of Biochemistry·W H Burgess, T Maciag
Jan 1, 1989·Annual Review of Physiology·D A FisherL Barajas
Feb 1, 1989·Journal of Cellular Biochemistry·D CaruelleD Barritault
Apr 1, 1989·British Medical Bulletin·J K Heath, A G Smith
Apr 1, 1989·Archives of Ophthalmology·W E SmiddyM B Sporn
May 1, 1989·The Journal of Clinical Investigation·T B ConnorM Lansing
Aug 1, 1989·The Journal of Cell Biology·P L McNeilP A D'Amore
Aug 1, 1989·Experimental Eye Research·P A CampochiaroL M Hjelmeland
Mar 17, 1988·Nature·M B Sporn, A B Roberts
Jan 1, 1989·Journal of Cellular Physiology·A HannekenL M Hjelmeland
Feb 1, 1987·Experimental Cell Research·L BassasF de Pablo
Jul 18, 1986·Cell·R RossD F Bowen-Pope
Jan 1, 1988·Journal of Clinical Gastroenterology·P Skov Olsen
Sep 4, 1987·Science·R Levi-Montalcini
Apr 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·S A LiptonP A D'Amore
Apr 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·I VlodavskyM Klagsbrun
Apr 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·D C BeebeP S Zelenka
Oct 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·V C BroudyJ W Adamson
Apr 1, 1986·Analytical Biochemistry·R R LobbJ W Fett

❮ Previous
Next ❯

Citations

Nov 1, 1993·Developmental Dynamics : an Official Publication of the American Association of Anatomists·R de Iongh, J W McAvoy
Mar 1, 1994·Journal of Cellular Physiology·F RenaudM Laurent
Jul 1, 1993·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·M KnorrJ Hoppe
Nov 14, 1997·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·M KnorrH J Thiel
Jul 15, 1994·Brain Research. Developmental Brain Research·J Scherer, J Schnitzer
Jun 19, 2003·Developmental Biology·Richard J W StumpJohn W McAvoy
Jan 1, 1993·Eye·A J BronR Blakytny
Dec 1, 1996·Differentiation; Research in Biological Diversity·M A Wride
May 1, 1993·The Journal of Cell Biology·Y IshizakiM C Raff
Feb 15, 2011·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Suresh Kumar GuptaSushma Srivastava
Mar 16, 2011·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·F J LovicuR U de Iongh
Jan 1, 1995·The European Journal of Neuroscience·K R HuxlinM R Bennett
Jan 1, 1991·Annals of the New York Academy of Sciences·J W McAvoyF J Lovicu
Nov 1, 1995·The British Journal of Ophthalmology·R M Knott, J V Forrester
Mar 1, 1995·The British Journal of Ophthalmology·N P JonesM E Boulton
Mar 5, 1998·The British Journal of Ophthalmology·G DuncanP D Davies
Feb 24, 2000·The British Journal of Ophthalmology·W R MeacockM R Stanford
Dec 17, 2008·Growth Factors·Laxmi IyengarFrank J Lovicu
Jun 1, 1997·Current Eye Research·P O DenkM Knorr
Feb 11, 1998·Journal of Cataract and Refractive Surgery·K KatoT Nagamoto
Mar 26, 2008·Journal of Cataract and Refractive Surgery·Katrien De KeyzerMarie-José Tassignon
Nov 1, 2005·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Valentina M Fokina, Elena I Frolova
Oct 27, 2010·Clinical & Experimental Ophthalmology·Hamdy AbdelkaderRaid G Alany
Jan 18, 2007·Archives of Medical Research·Elisa TamarizFederico Castro-Muñozledo
Aug 1, 1992·Current Opinion in Genetics & Development·M S SahaR M Grainger
Apr 7, 2005·Journal of Cataract and Refractive Surgery·Ulrike SponerChristian Skorpik
Jun 29, 2001·Experimental Eye Research·I O UmedaH Nishigori
Jun 2, 2009·Developmental Biology·Senthil S SaravanamuthuPeggy S Zelenka
Feb 7, 2001·Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society·B FeldmannB O Boehm
Aug 1, 1997·Developmental Dynamics : an Official Publication of the American Association of Anatomists·D S SakaguchiT A Reh

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.