Growth hormone administration: is it safe and effective for athletic performance

Endocrinology and Metabolism Clinics of North America
Vita BirznieceKen K Y Ho

Abstract

Human growth hormone (GH) is widely abused by athletes; however, there is little evidence that GH improves physical performance. Replacement of GH in GH deficiency improves some aspects of exercise capacity. There is evidence for a protein anabolic effect of GH in healthy adults and for increased lean body mass following GH, although fluid retention likely contributes to this increase. The evidence suggests that muscle strength, power, and aerobic exercise capacity are not enhanced by GH administration, however GH may improve anaerobic exercise capacity. There are risks of adverse effects of long-term abuse of GH. Sustained abuse of GH may lead to a state mimicking acromegaly, a condition with increased morbidity and mortality.

References

Oct 16, 1976·British Medical Journal·M NagulesparenJ S Jenkins
Nov 1, 1992·Acta Physiologica Scandinavica·J D MacDougallS A Atkinson
Nov 1, 1991·Acta Endocrinologica·J O JørgensenJ S Christiansen
Jan 1, 1991·Acta Paediatrica Scandinavica. Supplement·P H SönksenA Weissberger
Apr 1, 1991·The Journal of Clinical Endocrinology and Metabolism·J MøllerJ S Christiansen
Jan 1, 1990·Hormone Research·R C CuneoP H Sönksen
Jun 1, 1983·Pathology, Research and Practice·R A Brumback, C E Barr
Nov 1, 1982·The Journal of Clinical Endocrinology and Metabolism·P R Bratusch-MarrainR A DeFronzo
Aug 12, 1999·The Journal of Clinical Endocrinology and Metabolism·J GibneyD Russell-Jones
Jan 14, 2000·The Journal of Clinical Endocrinology and Metabolism·S FazioL Saccà
Nov 9, 2000·Neurology·P BrownS J Collins
Mar 7, 2001·The Journal of Clinical Endocrinology and Metabolism·J D WallaceC J Strasburger
Apr 5, 2002·The Journal of Clinical Endocrinology and Metabolism·Andrea F AttanasioUNKNOWN Hypoptiuitary Control and Complications Study International Advisory Board
Apr 5, 2002·The Journal of Clinical Endocrinology and Metabolism·Antonio CittadiniLuigi Saccà
Jan 10, 2003·The Journal of Clinical Endocrinology and Metabolism·C EhrnborgUNKNOWN GH-2000 Study Group
May 3, 2003·The Journal of Clinical Endocrinology and Metabolism·Johan SvenssonGudmundur Johannsson
Nov 7, 2003·The Journal of Clinical Endocrinology and Metabolism·M L HealyA M Umpleby
Dec 10, 2003·Mayo Clinic Proceedings·Deborah E Meyers, Ross C Cuneo
Feb 7, 2004·The Journal of Clinical Endocrinology and Metabolism·Raffaele ScarpaAnnamaria Colao
Aug 26, 2004·The Journal of Clinical Endocrinology and Metabolism·Brian A IrvingArthur Weltman
Apr 14, 2005·The Journal of Clinical Endocrinology and Metabolism·Gudmundur JohannssonKen K Y Ho
Aug 4, 2005·Sports Medicine·Mahmoud S El-SayedZeinab El-Sayed Ali
Jun 27, 2006·British Journal of Sports Medicine·M SaugyP Mangin
Nov 15, 2006·Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society·Jo K PerryPeter E Lobie
Feb 28, 2007·British Journal of Sports Medicine·James Young, Aresh Anwar
May 31, 2007·European Journal of Endocrinology·Alexandra KellerMartin Bidlingmaier
Jun 7, 2007·Annual Review of Psychology·Donald D PriceFabrizio Benedetti
Aug 24, 2007·Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society·Morton G BurtKen K Y Ho
Sep 6, 2007·Endocrine Reviews·James GibneyPeter H Sönksen

❮ Previous
Next ❯

Citations

Oct 22, 2010·Journal of Orofacial Orthopedics = Fortschritte Der Kieferorthopädie : Organ/official Journal Deutsche Gesellschaft Für Kieferorthopädie·Jens Christoph TürpRalf Johannes Radlanski
Sep 20, 2012·Endocrine·Leonidas H Duntas, Vera Popovic
Jul 1, 2011·Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine·Andrew Pipe
Mar 19, 2011·Current Opinion in Clinical Nutrition and Metabolic Care·Christopher C CossJames T Dalton
Jun 10, 2015·International Journal of Molecular Sciences·James KeaneBon Gray
Jun 7, 2011·Addictive Behaviors·Tom HildebrandtEric Hollander
Mar 19, 2014·Medical Hypotheses·J P LoennekeM G Bemben
May 12, 2011·Human & Experimental Toxicology·Matthew J GeraciPeter Davis
Jan 22, 2011·Drug Testing and Analysis·Mario ThevisWilhelm Schänzer

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cancer Metabolism

In order for cancer cells to maintain rapid, uncontrolled cell proliferation, they must acquire a source of energy. Cancer cells acquire metabolic energy from their surrounding environment and utilize the host cell nutrients to do so. Here is the latest research on cancer metabolism.

Related Papers

The Journal of Clinical Endocrinology and Metabolism
Linda J WoodhouseShalender Bhasin
Journal of Strength and Conditioning Research
Jay R HoffmanAlan D Rogol
Drug and Alcohol Dependence
Anna PeterssonIngemar Thiblin
© 2021 Meta ULC. All rights reserved