Growth impairment and adrenal suppression on low-dose inhaled beclomethasone

Journal of Paediatrics and Child Health
Savitha D ShenoyDeclan Cody

Abstract

Growth impairment and adrenal suppression secondary to inhaled corticosteroids (ICS) is a well-recognised phenomenon. We report a 13-year-old boy, treated long-term for asthma, who presented with short stature while on low-dose inhaled corticosteroid (beclomethasone 200 microg/d). Investigations revealed evidence of severe adrenal suppression. Weaning off the steroid treatment resulted in recovery of adrenal activity and rapid growth. While low-dose ICS are normally considered to have few side effects, this case illustrates the extreme variability of individual sensitivity and the need for careful surveillance of all children treated with long-term steroids.

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Citations

Aug 27, 2011·Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology·Alexandra AhmetSheldon Spier
Nov 8, 2014·Clinical Endocrinology·Daniel B HawcuttRosalind L Smyth
Sep 15, 2010·Clinical Pediatrics·Yaa Kumah-Crystal, Jefferson P Lomenick

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